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ProteomicsChronic polypharmacy, monotherapy, and deprescribing: Understanding complex effects on the hepatic proteome of aging mice
Polypharmacy (use of 5 or more concurrent medications) is highly prevalent among older adults to manage chronic diseases and is linked to adverse geriatric outcomes, including physical and cognitive functional impairments, falls, frailty, hospitalization, and mortality. Deprescribing (withdrawal) i...
ORGANISM(S): Mus musculus (Mouse) 
2024-11-12 | PXD049469 | Pride
Aging Deprescribing Citalopram Mouse Simvastatin Oxybutynin Metoprolol Polypharmacy Dia Drug response Lc-ms Oxycodone Liver 
UnknownPopulation structure and evolution of resistance to acetolactate synthase (ALS)-inhibitors in Amaranthus tuberculatus in Italy.
Not available
S-EPMC8251816 | biostudies-literature
UnknownCascaded-mode interferometers: Spectral shape and linewidth engineering.
Not available
S-EPMC11922044 | biostudies-literature
UnknownThin-film lithium niobate terahertz differential field detectors with a bandwidth reaching 3 terahertz.
Not available
S-EPMC12500990 | biostudies-literature
UnknownGenomics and biochemical analyses reveal a metabolon key to β-L-ODAP biosynthesis in Lathyrus sativus.
Not available
S-EPMC9935904 | biostudies-literature
TranscriptomicsSimultaneous Host-Pathogen transcriptome analysis during Granulibacter bethesdensis infection of normal and chronic granulomatous disease neutrophils
Polymorphonuclear leukocytes (PMN) from patients with chronic granulomatous disease (CGD) fail to produce microbicidal concentrations of reactive oxygen species due to mutations in NOX2. Patients with CGD suffer from severe, life-threatening infections and inflammatory complications. Granulibacter...
ORGANISM(S): Homo sapiens 
2015-09-08 | E-GEOD-55849 | biostudies-arrayexpress
UnknownGlobal Commitments to Conserving and Monitoring Genetic Diversity Are Now Necessary and Feasible.
Not available
S-EPMC8407967 | biostudies-literature
UnknownAIMSurv: First pan-European harmonized surveillance of Aedes invasive mosquito species of relevance for human vector-borne diseases.
Not available
S-EPMC9930523 | biostudies-literature
UnknownGlobal maps of soil temperature.
Not available
S-EPMC9303923 | biostudies-literature
UnknownLipoprotein(a) and Benefit of PCSK9 Inhibition in Patients With Nominally Controlled LDL Cholesterol.
Not available
S-EPMC8822604 | biostudies-literature
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