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Polypharmacy (use of 5 or more concurrent medications) is highly prevalent among older adults to manage chronic diseases and is linked to adverse geriatric outcomes, including physical and cognitive functional impairments, falls, frailty, hospitalization, and mortality. Deprescribing (withdrawal) i...
ORGANISM(S): Mus musculus (Mouse) 
2024-11-12 | PXD049469 | Pride
The use of polypharmacy (5 or more concurrent medications) is common in older patients, particularly those with cardiovascular diseases. However, polypharmacy is associated with adverse geriatric outcomes, including increased risks in fall and frailty. Both ageing and sex influence pharmacological r...
ORGANISM(S): Mus musculus (Mouse) 
2025-06-02 | PXD057325 | Pride
Genomics
Effects of chronic polypharmacy and deprescribing on the hepatic transcriptome of aging mice
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