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ProteomicsInterval-based secretomics unravels the time-dependent acute phase response in hepatocyte model systems
Mass spectrometry based secretomics approaches preferentially utilize serum-free culture conditions to circumvent serum induced interference and enable sufficient analytical depth. However, this negatively affects a wide range of cellular functions and thus reduces the biological relevance. Moreover...
ORGANISM(S): Homo sapiens (Human) 
2022-05-04 | PXD027821 | Pride
Il1b Heparg Shedding Secretomics Liver Acute-phase response Interval-based secretomics Il6 Hepg2 
GenomicsDNA methylome analysis of leader cells and follower cells derived from the H1299 NSCLC cell line
DNA methylome analysis of leader cells and follower cells derived from the H1299 NSCLC cell line
PRJNA613206 | ENA
UnknownAn extensin-rich matrix lines the carinal canals in Equisetum ramosissimum, which may function as water-conducting channels.
Not available
S-EPMC3143055 | biostudies-literature
TranscriptomicsInhibition of Met results in concomitant inhibition of Akt and STAT3 signaling pathways, while abrogation of negative feedback permits Erk reactivation
Amplification and activation of the Met receptor tyrosine kinase occurs up to 23% of gastric cancers, suggesting that Met is a therapeutic target in these cancers. However, the steady-state signaling events that occur during chronic Met activation, and mechanisms for resistance to Met small-molecul...
ORGANISM(S): Homo sapiens 
2014-05-19 | E-GEOD-54532 | biostudies-arrayexpress
ProteomicsA non-canonical vitamin K cycle is a potent ferroptosis suppressor
Raw files corresponding to LC-MS-based relative quantification of oxidized lipids in Pfa1 cells and mouse liver samples subjected to ferroptosis. Data were acquired in parallel reaction monitoring (PRM) MS/MS mode.
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2022-05-19 | MSV000089489 | MassIVE
UnknownEffects of Scalable, Wordless, Short, Animated Storytelling Videos on Flu Vaccine Hesitancy in China: Nationwide, Single-Blind, Parallel-Group, Randomized Controlled Trial.
Not available
S-EPMC12385612 | biostudies-literature
TranscriptomicsPandemic Swine-Origin H1N1 Influenza A Virus Isolates Show Heterogeneous Virulence in Macaques
This study used virological, histological, immunological and global gene expression to compare the virlence of two newly emerged 2009 H1N1 isolates (A/Mexico/InDRE4487/2009 and A/Mexico/4108/2009) and current seasonal H1N1 influenza strain (A/Kawasaki/UTK-4/2009) in experimentally infected cynomolgu...
ORGANISM(S): Macaca fascicularis 
2011-08-29 | E-GEOD-31694 | biostudies-arrayexpress
UnknownDeletion 17q12 is a recurrent copy number variant that confers high risk of autism and schizophrenia.
Not available
S-EPMC2978962 | biostudies-literature
TranscriptomicsAcute host transcriptonal response to A/Texas/36/91 influenza and A/Texas/36/91 influenza containing the NS1 gene from r1918 in A549 cells
The M-bM-^@M-^\Spanish influenzaM-bM-^@M-^] of 1918 claimed an unprecedented number of lives, yet the determinants of virulence for this virus are still not fully understood. Here, we used functional genomics and an in vitro human lung epithelial cell infection model to define the global host transc...
ORGANISM(S): Homo sapiens 
2012-05-13 | E-GEOD-37829 | biostudies-arrayexpress
UnknownAnimated, video entertainment-education to improve vaccine confidence globally during the COVID-19 pandemic: an online randomized controlled experiment with 24,000 participants.
Not available
S-EPMC8857749 | biostudies-literature
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