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TranscriptomicsHuman scrotum and labia majora samples treated with DHT and/or AZA
Human scrotum and labia majora samples treated with DHT and/or AZA A compound treatment design type is where the response to administration of a compound or chemical (including biological compounds such as hormones) is assayed. Compound Based Treatment: dihydrotestosterone (DHT), 5-aza-deoxy-cytidin...
ORGANISM(S): Homo sapiens 
2009-05-20 | E-GEOD-11847 | biostudies-arrayexpress
TranscriptomicsTranslational profiling of HEK293 cells exposed to cold shock (32 degrees C) and untreated (37 degrees C)
This experiment investigates the effect of mild cold-shock (32 degrees C, 24 hours) on the translatome of human HEK293 cells. After cold-shock, cells were treated with cycloheximide to block elongation, then sucrose density gradients were used to separate post-nuclear extracts into polysome and subp...
ORGANISM(S): Homo sapiens 
2017-02-23 | E-MTAB-5437 | biostudies-arrayexpress
UnknownOpen-Circuit Photovoltage Exceeding 950 mV with an 840 mV Average at Sb2S3-Thianthrene+/0 Junctions Enabled by Thioperylene Anhydride Back Contacts.
Not available
S-EPMC7364746 | biostudies-literature
TranscriptomicsTop3M-NM-2 is an RNA topoisomerase that works with Fragile X syndrome protein to promote synapse formation
Topoisomerases are crucial to solve DNA topological problems, but they have not been linked to RNA metabolism. Here we show that human topoisomerase 3M-NM-2 (Top3M-NM-2) is an RNA topoisomerase that biochemically and genetically interacts with FMRP, a protein deficient in Fragile X syndrome and know...
ORGANISM(S): Homo sapiens 
2013-08-04 | E-GEOD-47502 | biostudies-arrayexpress
UnknownCapture Hi-C identifies putative target genes at 33 breast cancer risk loci.
Not available
S-EPMC5847529 | biostudies-literature
TranscriptomicsDefinition of the Pseudomonas aeruginosa Anr and Dnr Regulons
The anaerobic metabolism of the opportunistic pathogen Pseudomonas aeruginosa is important for growth and survival during persistent infections. The two Fnr-type transcription factors Anr and Dnr regulate different parts of the underlying network. Both are proposed to bind to a non-distinguishable D...
ORGANISM(S): Pseudomonas aeruginosa 
2010-07-07 | E-GEOD-17179 | biostudies-arrayexpress
ProteomicsThe potential role of the collagen gene family in congenital Zika syndrome: A systems biology approach
In this study, we have generated genomic, transcriptomic and proteomic data from the blood and post-mortem brain samples of eight neonates with confirmed ZIKV infection during pregnancy and with no congenital genetic diseases nor another STORCH group vertical transmission.
ORGANISM(S): Homo sapiens (Human) 
2020-05-26 | PXD012461 | Pride
Zika  microcephaly  systems biology  collagen 
ProteomicsMetaomic study on the ecophysiological cascade underlaying seasonal N2O emissions
Nina Roothans et al.(2024) combined long-term, metagenomically resolved metaproteomics and ex situ kinetic characterizations to elucidate the ecophysiology of an N2O-emitting wastewater treatment plant community. The integration of these data enabled the identification of a cascade of environmental ...
ORGANISM(S): Microthrix Candidatus Accumulibacter phosphatis Nitrosomonas sp. Nitrospira sp. 
2025-02-21 | PXD051095 | Pride
Wastewater treatment plants Microbes Shotgun proteomics Metaproteomics 
TranscriptomicsInnate immune pathways in afferent lymph following vaccination with poly(I:C) -containing liposomes
Many modern vaccines use defined adjuvants to stimulate the innate immune system and shape the adaptive immune response. The exact nature of these innate signals and whether immune differentiation can originate within the periphery is not known. In the present study we used an ovine lymphatic cannul...
ORGANISM(S): Ovis aries 
2013-08-01 | E-GEOD-38533 | biostudies-arrayexpress
TranscriptomicsA conserved two-component signal transduction system controls the response to phosphate starvation in Bifidobacterium breve UCC2003
This work reports on the identification and molecular characterization of a two-component regulatory system (2CRS), encoded by phoRP in Bifidobacterium breve UCC2003, which controls the response to phosphate (Pi) starvation. The response regulator PhoP was shown to bind to the promoter region of pst...
ORGANISM(S): Bifidobacterium breve UCC2003 
2012-09-06 | E-GEOD-34983 | biostudies-arrayexpress
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