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ProteomicsIdentification of the protein interaction network of STAG2 protein isoforms with inclusion and exclusion of exon32
This study involves the identification of specific interactors for STAG2ex32+ and STAG2ex32delta. Plasmids expressing YFP-STAG2 isoforms were transfected into HCT116OsTIR cells using untransfected cells as mock control. 40h post transfection, whole cell lysates were extracted and STAG2 isoforms were...
ORGANISM(S): Homo sapiens (Human) 
2023-05-04 | PXD041975 | Pride
Ap-ms 
ProteomicsIdentification of the protein interaction network of Stag proteins
This study involves the identification of specific Stag1 interactors with and without Cohesin loss. Stag1 was immunoprecipiated from human HCT116 cells, under 4 treatments - untreated (UTR), Non-specific siRNA treatment (SiCON), SA1 siRNA treatment (SiSA1) and Auxin treatment for Cohesin loss (IAA)....
ORGANISM(S): Homo sapiens (Human) 
2023-04-18 | PXD024354 | Pride
Human Ap-ms Lc-ms Lfq Stag 
TranscriptomicsChIP-seq of histone H3 and H3K9me2 in WT and dbl2 mutant fission yeast
The aim was to compare the levels of histone H3 dimethylation at lysine 9 (H3K9me2) in wild-type and dbl2 knock-out Schizosaccharomyces pombe cells. Fission yeast cultures were grown in the complex YES medium to exponential phase and chromatin immunoprecipitation was carried out using anti-H3 and an...
ORGANISM(S): Schizosaccharomyces pombe 
2020-10-02 | E-MTAB-9619 | biostudies-arrayexpress
UnknownRandomized phase II study of erlotinib in combination with placebo or R1507, a monoclonal antibody to insulin-like growth factor-1 receptor, for advanced-stage non-small-cell lung cancer.
Not available
S-EPMC5320944 | biostudies-literature
TranscriptomicsGenome-wide characterization of maize small RNA loci and their regulation in the required to maintain repression6-1 (rmr6-1) mutant and long-term abiotic stresses
Endogenous small RNAs (sRNAs) contribute to gene regulation and genome homeostasis but their activities and functions are incompletely known. The maize genome has a high number of transposable elements (TEs; almost 85%), some of which spawn abundant sRNAs. We performed sRNA and total RNA sequencing ...
ORGANISM(S): Zea mays 
2016-01-20 | E-GEOD-70487 | biostudies-arrayexpress
ProteomicsNeuronal Hyperactivity in Neurons Derived from Individuals with Grey Matter Heterotopia
Periventricular heterotopia (PH), the most common form of grey matter heterotopia, represents a cortical malformation that is often associated with developmental delay and drug-resistant seizures1,2. The detailed neurophysiological underpinnings of PH symptoms in humans remain, however, elusive. Hum...
ORGANISM(S): Homo sapiens (Human) 
2025-01-13 | PXD038760 | Pride
Human Neuronal hyperactivity. fat4 Qe plus Periventricular heterotopia O cerebral rganoids Dchs1 
TranscriptomicsGene expression changes in Tulasnella calospora- Serapias vomeracea mycorrhizal protocorms compared to Tulasnella calospora free-living mycelium
Illumina HiSeq technology was used to generate mRNA profiles from Tulasnella calospora mycorrhizal protocorms compared to free-living mycelium . Protocorms and control mycelium were harvested after 30 days and used for RNA extraction. Reads of 2X100bp were generated and aligned to Tulasnella calospo...
ORGANISM(S): Tulasnella calospora 
2015-02-06 | E-GEOD-63869 | biostudies-arrayexpress
TranscriptomicsTranscriptomic signatures of risk genes implicated in psychiatric disorders during neuronal differentiation
Susceptibility genes for Autism Spectrum Disorder (ASD), Fragile X Syndrome (FXS), monogenetic disorders with intellectual disabilities (ID) or schizophrenia (SCZ) converge on processes related to neuronal function and differentiation. Furthermore, ASD risk genes are enriched for FMRP (Fragile X Men...
ORGANISM(S): Homo sapiens 
2016-06-01 | E-GEOD-69838 | biostudies-arrayexpress
TranscriptomicsGene expression changes in Oidiodendron maius- Vaccinium myrtillus mycorrhizal roots compared to Oidiodendron maius free-living mycelium
Illumina HiSeq technology was used to generate mRNA profiles from Oidiodendron maius mycorrhizal roots compared to free-living mycelium . Mycorrhizal roots and control mycelium were harvested after 45 days and used for RNA extraction. Reads of 2X100bp were generated and aligned to Oidiodendron maius...
ORGANISM(S): Oidiodendron maius 
2015-02-06 | E-GEOD-63922 | biostudies-arrayexpress
UnknownA Tunguska sized airburst destroyed Tall el-Hammam a Middle Bronze Age city in the Jordan Valley near the Dead Sea.
Not available
S-EPMC8452666 | biostudies-literature
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