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ProteomicsThe host exosome biogenesis pathway is essential for human cytomegalovirus virion assembly and egress
Human Cytomegalovirus (HCMV) infects over 50% of humans, is a leading cause of congenital birth defects, and poses serious risks for immuno-compromised individuals. To expand the molecular knowledge governing virion assembly and egress, we initiated a proteomics-based investigation and identified a ...
ORGANISM(S): Homo sapiens (Human) Human cytomegalovirus (strain AD169) (HHV-5) (Human herpesvirus 5) 
2021-02-22 | PXD015081 | Pride
Vamp3 Herpesvirus Proteomics Exosome Extracellular vesicle Cmv Viral infection Egress Virion assembly Human cytomegalovirus 
OtherSirtuin 4 is a lipoamidase regulating pyruvate dehydrogenase complex activity.
Data from ProteomeXchange, PXD ID: PXD001447. Experiment: SIRT4_MITO_MOCK1, file: SIRT4_MITO_MOCK1_05.mzml. Published as part of Cell. 2014 Dec 18;159(7):1615-25 . From the Abstract: {{i}} ... Here, we establish SIRT4 as a cellular lipoamidase that regulates the pyruvate dehydrogenase complex (PDH)...
ORGANISM(S): Homo_sapiens_viruses, Human 
GPM32320006423 | GPMDB
Resource Reanalysis 
ProteomicsApoA-I [human] (CSL112) infusion increases LCAT levels in HDL particles and promotes reverse cholesterol transport
Background: High-density lipoprotein (HDL)-cholesterol is inversely correlated with cardiovascular risk, but increasing its circulating concentration is insufficient to prevent adverse cardiovascular outcomes. Instead, the emerging paradigm is on increasing the function of HDL and its major protein...
ORGANISM(S): Homo sapiens (Human) 
2025-06-16 | PXD057196 | Pride
Lecithin-cholesterol acyl transferase Proteome Csl112 High-density lipoprotein Acute myocardial infarction 
OtherExtracellular remodelling during oncogenic Ras-induced epithelial-mesenchymal transition facilitates MDCK cell migration.
PeptideAtlas ID: PAe003680. Original data file: O070224-30.mgf. Data published as part of J Proteome Res. 2010 Feb 5;9(2):1007-19 . From the Abstract: {{i}}... To gain insights into extracellular mediators associated with EMT, we conducted an extensive proteomic analysis of the secretome from MDCK ...
ORGANISM(S): Dog, Canine_adenovirus, Canine_calicivirus, Canine_distemper_virus, Canine_minute_virus, Canine_oral_papillomavirus, Canine_papillomavirus_2, Canine_papillomavirus___3, Canine_papillomavirus___4, Canine_parvovirus 
GPM11210000341 | GPMDB
ProteomicsAP-MS analysis of sirtuin-4 interactions in human fibroblasts
Sirtuins (SIRTs) form a critical family of nicotinamide adenine dinucleotide (NAD)-dependent enzymes that govern genome regulation, metabolism, and aging. Despite conserved deacetylase domains, SIRTs4-7 have little to no deacetylase activity, and a robust catalytic activity for mitochondrial SIRT4 h...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-03-04 | MSV000079557 | MassIVE
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