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ProteomicsWDFY2 restrains matrix metalloproteinase secretion and cell invasion by controlling VAMP3-dependent recycling
The endosomal FYVE- and WD40-domain-containing protein WDFY2 has been assigned a function as tumor suppressor, but its functional mechanism has remained elusive. Here we have used confocal, widefield and super-resolution fluorescence microscopy to show that WDFY2 localizes to the base of retromer-co...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-07-23 | MSV000084122 | MassIVE
ProteomicsWDFY2 restrains matrix metalloproteinase secretion and cell invasion by controlling VAMP3-dependent recycling
The endosomal FYVE- and WD40-domain-containing protein WDFY2 has been assigned a function as tumor suppressor, but its functional mechanism has remained elusive. Here we have used confocal, widefield and super-resolution fluorescence microscopy to show that WDFY2 localizes to the base of retromer-co...
ORGANISM(S): Homo sapiens (Human) 
2019-07-02 | PXD013480 | Pride
Vamp3 Endosome Ptdins3p Cell invasion Recycling Wdfy2 
GenomicsRegulation of gene expression by miR-124 or VAMP3 in SK-N-SH cells
Regulation of gene expression by miR-124 or VAMP3 in SK-N-SH cells
PRJNA1003080 | ENA
TranscriptomicsRegulation of gene expression by miR-124 or VAMP3 in SK-N-SH cells
To study how miR-124 and VAMP3 may regulate human neuroblastoma, thee human neuroblastoma cell line SK-N-SH were transiently transfected to overexpress miR-124 or VAMP3, and total RNA was isolated 48 hours after transfection and subject to RNA-seq.
ORGANISM(S): Homo sapiens 
2023-10-23 | GSE240277 | GEO
UnknownmiR-124 and VAMP3 Act Antagonistically in Human Neuroblastoma.
Not available
S-EPMC10573497 | biostudies-literature
UnknownEndosomal sorting of VAMP3 is regulated by PI4K2A.
Not available
S-EPMC4150061 | biostudies-literature
UnknownEndocytic BDNF secretion regulated by Vamp3 in astrocytes.
Not available
S-EPMC8551197 | biostudies-literature
ProteomicsGrowth factor-mediated regulation of neuronal exosome release depends on VAMP3/cellubrevin
Extracellular vesicles (EVs) are small membrane-derived vesicles that shuttle proteins or nucleic acids between glia and neurons, thereby promoting neuronal survival and plasticity in the CNS. Exosomes are small EVs (40-150 nm) that are derived from multi-vesicular bodies (MVBs) of the endo-lysosoma...
ORGANISM(S): Rattus norvegicus (Rat) 
2020-02-06 | PXD014401 | Pride
Vamp3 Rat Neurons Exosome 
UnknownMultifunctional regulation of VAMP3 in exocytic and endocytic pathways of RBL-2H3 cells.
Not available
S-EPMC9388853 | biostudies-literature
UnknownPhosphorylation of VAMP3 couples IL-6 exocytosis to dendritic cell activation.
Not available
S-EPMC12579954 | biostudies-literature
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