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ProteomicsTransposable elements drive regulatory and functional innovation of F box genes
Protein domains of transposable elements (TEs) and viruses increase the protein diversity of host genomes by recombining with other protein domains. By screening 10 million eukaryotic proteins, we identified several domains that define multi-copy gene families and frequently co-occur with TE/viral d...
ORGANISM(S): Caenorhabditis elegans 
2024-12-16 | PXD048290 | Pride
Lc-ms/ms 
TranscriptomicsComparison of gene expression in 23 Cryptococcus gattii isolates
An array analysis of C. gattii (C. bacillosporus), intended to identify loci associated with the hypervirulence of the Vancouver Island Outbreak (VIO). 23 C. gattii isolates, representing both VIO strains and control strains, were grown for 24 hours in mammalian macrophages. RNA was isolated and g...
ORGANISM(S): Cryptococcus bacillisporus 
2010-05-15 | E-GEOD-17052 | biostudies-arrayexpress
ProteomicsZBTB48 is both a vertebrate telomere-binding protein and a transcriptional activator
Telomeres constitute the ends of linear chromosomes and together with the shelterin complex form a structure essential for genome maintenance and stability. In addition to the constitutive binding of the shelterin complex, other direct, yet more transient interactions are mediated by the CST complex...
ORGANISM(S): Homo sapiens (Human) 
2017-05-11 | PXD006074 | Pride
Zbtb48  hela  u2os  knock-out 
UnknownQuantitative [18F]florbetapir PET/CT may identify lung involvement in patients with systemic AL amyloidosis.
Not available
S-EPMC8202062 | biostudies-literature
UnknownPreventive Trichuris suis ova (TSO) treatment protects immunocompetent rabbits from DSS colitis but may be detrimental under conditions of immunosuppression.
Not available
S-EPMC5705695 | biostudies-literature
ProteomicsBaculovirus-mediated expression of a maleness gene in female Anopheles gambiae cells
Rising global temperatures are expected to increase the burden of infectious diseases, including the expansion of mosquito-borne illnesses into new regions. The Anopheles mosquito, the vector of malaria, is a highly sexually dimorphic species; only females require blood meals for egg production and ...
ORGANISM(S): Anopheles gambiae (African malaria mosquito) 
2026-08-24 | PXD070102 | Pride
Lc-ms/ms 
UnknownA Single Shot Pre-fusion-Stabilized Bovine RSV F Vaccine is Safe and Effective in Newborn Calves with Maternally Derived Antibodies.
Not available
S-EPMC7349975 | biostudies-literature
ProteomicsPhylointeractomics reconstructs functional evolution of protein binding
Molecular phylogenomics investigates evolutionary relationships based on genomic data. However, despite genomic sequence conservation, changes in protein interactions can occur relatively rapidly and may cause strong functional diversification. To investigate such functional evolution, we here combi...
ORGANISM(S): Bos taurus (Bovine) Homo sapiens (Human) Mus musculus (Mouse) Gallus gallus (Chicken) Sus scrofa domesticus (domestic pig) Rattus norvegicus (Rat) Taeniopygia guttata (Zebra finch) (Poephila guttata) 
2017-02-15 | PXD005517 | Pride
Telosome Interactomics Lc-msms 
ProteomicsNpl3 stabilizes R-loops at telomeres to prevent accelerated replicative senescence
Telomere shortening rates must be regulated to prevent premature replicative senescence. TERRA R-loops become stabilized at critically short telomeres to promote their elongation through homology-directed repair (HDR), thereby counteracting senescence onset. Using a non-bias proteomic approach to id...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2020-01-31 | PXD016772 | Pride
Lc-ms/ms  telomere  pulldown 
UnknownPoint-of-care Intestinal Ultrasound in IBD Patients: Disease Management and Diagnostic Yield in a Real-world Cohort and Proposal of a Point-of-care Algorithm.
Not available
S-EPMC9089417 | biostudies-literature
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