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ProteomicsWild-type and Pgrmc1 KO mouse liver membrane LC-MSMS with isobaric tagging
Progesterone receptor membrane component 1 (PGRMC1) is a heme binding protein implicated in a wide range of cellular functions. Our previous studies showed that PGRMC1 binds to cytochromes P450 in yeast and mammalian cells and promotes activity of these enzymes. Recently, the paralog PGRMC2 was show...
ORGANISM(S): Mus musculus (Mouse) 
2022-02-16 | PXD028238 | Pride
Lc-msms Mouse Tmt Membrane Pgrmc1 Liver Isobaric tag 
ProteomicsLC-MSMS with isobaric tagging of Pgrmc1 KO mouse liver membranes expressing Flag-Pgrmc1 or Y113F Flag-Pgrmc1
Progesterone receptor membrane component 1 (PGRMC1) is a heme binding protein implicated in a wide range of cellular functions. Our previous studies showed that PGRMC1 binds to cytochromes P450 in yeast and mammalian cells and promotes activity of these enzymes. Recently, the paralog PGRMC2 was show...
ORGANISM(S): Mus musculus (Mouse) 
2022-02-16 | PXD028288 | Pride
Lc-msms Mouse Tmt Y113f flag-pgrmc1 Membrane Pgrmc1 Flag-pgrmc1 Liver Isobaric tag 
UnknownTowards Genotype-Specific Care for Chronic Hepatitis B: The First 6 Years Follow Up From the CHARM Cohort Study.
Not available
S-EPMC7445891 | biostudies-literature
UnknownStereotactic Body Radiotherapy for Primary Prostate Cancer.
Not available
S-EPMC6069023 | biostudies-literature
ProteomicsN-glyco db/db mouse kidney - N-glycosylation proteome enrichment analysis in kidney reveals differences between diabetic mouse models
N-glycosylated proteome of db/db diabetic mice with diabetic nephropathy, additional effect of insulin on db/db mice.
ORGANISM(S): Mus musculus (Mouse) 
2016-12-13 | PXD003349 | Pride
Db/db mice Mass spectrometry N-glycosylation N-glyco capture Insulin Diabetic nephropathy Diabetes 
ProteomicsLiraglutide effect on STZ Mouse Kidney with diabetic nephropathy
The effect of liraglutide on the kidney proteome in the STZ mouse model compared to healthy and STZ diabetic control groups.
ORGANISM(S): Mus musculus (Mouse) 
2019-01-18 | PXD003007 | Pride
Liraglutide Kidney Proteome Stz Shotgun Diabetes nephropathy Label-free 
GenomicsEpi4K: Gene Discovery in 4,000 Epilepsy Genomes

The Epi4K project began in 2011 as an international, multi-center study that seeks to identify and characterize the genetic bases of complex epilepsies. The Center without Walls Epi4K project includes three cores and four scientific projects, as well as a steering committee comprised of the prima...

phs000653.v1.p1 | EGA
MetabolomicsDietary restriction of cysteine and methionine sensitizes gliomas to ferroptosis and induces alterations in energetic metabolism

Ferroptosis is mediated by lipid peroxidation of phospholipids containing polyunsaturated fatty acyl moieties. Glutathione, the key cellular antioxidant capable of inhibiting lipid peroxidation via the activity of the enzyme glutathione peroxidase 4 (GPX-4), is generated directly from the sulfur-...

2023-01-11 | MTBLS5959 | MetaboLights
UnknownMucosa-associated invariant T cells link intestinal immunity with antibacterial immune defects in alcoholic liver disease.
Not available
S-EPMC5890654 | biostudies-literature
UnknownPPM1D Mosaic Truncating Variants in Ovarian Cancer Cases May Be Treatment-Related Somatic Mutations.
Not available
S-EPMC5072371 | biostudies-literature
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