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UnknownActivating NOTCH1 Mutations Define a Distinct Subgroup of Patients With Adenoid Cystic Carcinoma Who Have Poor Prognosis, Propensity to Bone and Liver Metastasis, and Potential Responsiveness to Notch1 Inhibitors.
Not available
S-EPMC5456373 | biostudies-literature
UnknownEnhanced nutrient transport improves the depth-dependent properties of tri-layered engineered cartilage constructs with zonal co-culture of chondrocytes and MSCs.
Not available
S-EPMC5559709 | biostudies-literature
ProteomicsThermal Liquid Biopsy for Early Colorectal Cancer Diagnosis integrating mass spectrometry proteomic biomarker discovery
Colorectal cancer (CRC) is one of the most prevalent cancers worldwide. When detected early, mortality rates can be significantly reduced, as surgical intervention in early stages often leads to curative outcomes. However, current biomarkers, such as carcinoembryonic antigen (CEA), have limitations ...
ORGANISM(S): Homo sapiens (Human) 
2026-01-11 | PXD064655 | Pride
Biomarkers  classification model  colorectal cancer (crc)  diagnosis  machine learning algorithms  mass spectrometry (ms)  prognosis  thermal liquid biopsy (tlb) 
UnknownImproved Survival for Children and Young Adults With T-Lineage Acute Lymphoblastic Leukemia: Results From the Children's Oncology Group AALL0434 Methotrexate Randomization.
Not available
S-EPMC6366301 | biostudies-literature
UnknownPlasminogen binding by group A streptococcal isolates from a region of hyperendemicity for streptococcal skin infection and a high incidence of invasive infection.
Not available
S-EPMC343955 | biostudies-literature
ProteomicsChronic polypharmacy, monotherapy, and deprescribing: Understanding complex effects on the hepatic proteome of aging mice
Polypharmacy (use of 5 or more concurrent medications) is highly prevalent among older adults to manage chronic diseases and is linked to adverse geriatric outcomes, including physical and cognitive functional impairments, falls, frailty, hospitalization, and mortality. Deprescribing (withdrawal) i...
ORGANISM(S): Mus musculus (Mouse) 
2024-11-12 | PXD049469 | Pride
Aging Deprescribing Citalopram Mouse Simvastatin Oxybutynin Metoprolol Polypharmacy Dia Drug response Lc-ms Oxycodone Liver 
UnknownN-Terminal Finger Stabilizes the S1 Pocket for the Reversible Feline Drug GC376 in the SARS-CoV-2 Mpro Dimer.
Not available
S-EPMC8061786 | biostudies-literature
MetabolomicsGeographic variation of mutagenic exposures in kidney cancer genomes

International differences in the incidence of many cancer types indicate the existence of carcinogen exposures that have not been identified by conventional epidemiology yet potentially make a substantial contribution to cancer burden1. This pertains to clear cell renal cell carcinoma (ccRCC), fo...

2024-03-26 | MTBLS9394 | MetaboLights
UnknownStructure and dynamics of the proton-selective histidine and the gating tryptophan in an inward rectifying hybrid influenza B and A virus M2 proton channel.
Not available
S-EPMC11290064 | biostudies-literature
UnknownPhysical activity postpartum: A systematic review and quality appraisal of clinical guidelines.
Not available
S-EPMC12949317 | biostudies-literature
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