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TranscriptomicsTranscription profiling of spinal cord and oculomotor neurons from control and SOD1 mutant mice to test the hypothesis that the oculomotor neurons are intrinsically protected in amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) spares the ocular motor system. In this study, we tested the hypothesis that the oculomotor neurons are intrinsically protected in ALS. Using high-density cDNA microarrays, we examined the transcriptome of oculomotor nuclei and spinal cords in mice expressing a hu...
ORGANISM(S): Mus musculus 
2007-06-28 | E-GEOD-3343 | biostudies-arrayexpress
UnknownThe chemerin knockout rat reveals chemerin dependence in female, but not male, experimental hypertension.
Not available
S-EPMC6219827 | biostudies-literature
TranscriptomicsTranscription profiling of rat spinal cord and oculomotor nucleus samples from animals aged 6, 18 and 30 months
Some of the most common neurodegenerative disorders have a strong association with aging. Curiously, these conditions tend to involve specific areas of the central and peripheral nervous system, at least initially. For example, amyotrophic lateral sclerosis preferentially targets spinal motor neuron...
ORGANISM(S): Rattus norvegicus 
2007-10-10 | E-GEOD-3305 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat extraocular muscle and extensor digitorum longus samples from animals aged 6, 18 and 30 months
The fast and constant activity of the extraocular muscles (EOMs) impose mechanical and metabolic stresses not typically seen in limb skeletal muscles. These functional properties may explain why EOMs seem to age at a faster rate than other skeletal muscles. Using high-density cDNA microarrays, thi...
ORGANISM(S): Rattus norvegicus 
2007-10-10 | E-GEOD-3309 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat posterior cricoarytenoid muscle from animals aged 6, 18 and 30 months
Sarcopenia is the decreased muscle mass and weakness associated with aging and a major cause of morbidity and mortality in the elderly. To what extent non-locomotive muscles are susceptible to this condition is unclear. For example, age affects laryngeal function (ventilation, airway protective refl...
ORGANISM(S): Rattus norvegicus 
2007-10-10 | E-GEOD-3310 | biostudies-arrayexpress
UnknownHammerhead: a compact 300 kV vacuum bushing.
Not available
S-EPMC12738623 | biostudies-literature
TranscriptomicsDeterminants of heat resistance in Escherichia coli AW1.7
Microarray hybridization of cDNA libraries obtained from exponentially growing or heat-shocked AW1.7 or GGG10 cultures was performed to compare gene expression of these two strains. Expression of selected genes from different functional groups was quantified by quantitative PCR (q-PCR). DnaK, 30S an...
ORGANISM(S): Escherichia coli 
2011-03-02 | E-GEOD-27607 | biostudies-arrayexpress
UnknownCo-designing and piloting educational materials with patients and healthcare providers for syncope in the emergency department.
Not available
S-EPMC10194231 | biostudies-literature
UnknownMotif-based zwitterionic peptides impact their structure and immunogenicity.
Not available
S-EPMC9491220 | biostudies-literature
TranscriptomicsGene profiling of heart atria in PI3K and Mst1 mouse models
We used microarrays to detail genome-wide gene expression underlying cardiac myocyte pathologies and identified candidate genes and specific pathways affecting cardiac myopathies Keywords: transgenics, cardiac disease analysis Mouse heart atria were dissected for RNA extraction and hybridisation on...
ORGANISM(S): Mus musculus 
2010-04-07 | E-GEOD-12420 | biostudies-arrayexpress
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