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ProteomicsQuantitative proteomic analysis of MCM3 in ThinPrep samples of patients with cervical preinvasive cancer
Triage methods for cervical cancer detection show moderate accuracy and present considerable false-negative and false-positive result rates. A complementary diagnostic parameter could help improve the accuracy of identifying patients who need treatment. A pilot study was performed using a targeted p...
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD042918 | Pride
Human Prm Mcm3 Cervical cancer 
ProteomicsIdentification and Characterization of MCM3 as a KEAP1 Substrate
KEAP1 is a substrate adaptor protein for a CUL3-based E3 ubiquitin ligase. Ubiquitylation and degradation of the antioxidant transcription factor NRF2 is considered the primary function of KEAP1; however, few other KEAP1 substrates have been identified. Because KEAP1 is altered in a number of human ...
ORGANISM(S): Homo sapiens (Human) 
2017-10-12 | PXD003929 | Pride
Hek293t Di-gly Apms Silac Label free quantification 
ProteomicsQuantitative proteomic analysis of MCM3 in ThinPrep samples of patients with cervical preinvasive cancer
Triage methods for cervical cancer detection show moderate accuracy and present considerable false-negative and false-positive result rates. A complementary diagnostic parameter could help improve the accuracy of identifying patients who need treatment. A pilot study was performed using a targeted p...
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD042919 | Pride
Human Mcm3 Cervical cancer Dda 
GenomicsThe effect of MCM3 gene knockdown on gene expression profile of tamoxifen-resistant breast cancer cell lines
The effect of MCM3 gene knockdown on gene expression profile of tamoxifen-resistant breast cancer cell lines
PRJNA626012 | ENA
TranscriptomicsThe effect of MCM3 gene knockdown on gene expression profile of tamoxifen-resistant breast cancer cell lines
MCM3 is one of several genes whose expression profile is markedly altered in tamoxifen-resistant breast cancer cell lines. We observed that increased MCM3 expression is associated with tamoxifen resistance. Knockdown of MCM3 resulted in increased susceptibility of tamoxifen-resistant breast cancer c...
ORGANISM(S): Homo sapiens 
2020-11-17 | GSE148878 | GEO
UnknownEvolutionary diversification of MCM3 genes in Xenopus laevis and Danio rerio.
Not available
S-EPMC4615024 | biostudies-literature
UnknownSystematic analysis of MCM3 in pediatric medulloblastoma via multi-omics analysis.
Not available
S-EPMC9483186 | biostudies-literature
UnknownDiagnostic and prognostic value of MCM3 and its interacting proteins in hepatocellular carcinoma.
Not available
S-EPMC7573876 | biostudies-literature
UnknownSequence specificity of an essential nuclear localization sequence in Mcm3.
Not available
S-EPMC11601334 | biostudies-literature
UnknownSequence specificity of an essential nuclear localization sequence in Mcm3.
Not available
S-EPMC11761085 | biostudies-literature
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