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ProteomicsHuman hela cells mitochondrial LC-MS
We extracted mitochondria from Hela cells which were treated with CCCP or DMSO for 2 h. The samples were digested by FAST and peptides were used DIA to analysis.
ORGANISM(S): Homo sapiens (Human) 
2020-01-29 | PXD016400 | Pride
Mitophagy 
ProteomicsProteomic analysis of the aggregated proteins in cerebral vessles from MYPT1SMKO mice
To comprehensively understand the mechanism by which MYPT1 modulates the phenotypic switching of VSMCs after ischemic stroke, the proteins of cortical small vessel from MYPT1SMKO and WT mice subjected to MCAO or sham group were collected for proteomic screening.
ORGANISM(S): Mus musculus (Mouse) 
2021-08-21 | PXD027869 | Pride
Mypt1 Ischemmic stroke Vsmc Bbb 
ProteomicsProteome-Wide Characterization of Phosphorylation-Induced Conformational and Stability Changes in Breast Cancer
Large-scale studies of protein phosphorylation have generally focused on determining the sites and stoichiometry of phosphorylated proteins derived from different biological specimens such as cell lines and tissue samples. While such information is important for understanding the role of phosphoryla...
ORGANISM(S): Homo sapiens (Human) 
2019-11-12 | PXD007916 | Pride
Protein stability Phosphorylation Human breast cancer Protein conformation 
UnknownInflammatory microenvironment and expression of chemokines in hepatocellular carcinoma.
Not available
S-EPMC4408458 | biostudies-literature
ProteomicsLarge-Scale Characterization of Phosphorylation-Induced Conformational and Stability Changes in Breast Cancer
Large-scale studies of protein phosphorylation have generally focused on determining the sites and stoichiometry of phosphorylated proteins derived from different biological specimens such as cell lines and tissue samples. While such information is important for understanding the role of phosphoryla...
ORGANISM(S): Homo sapiens (Human) 
2019-11-12 | PXD007878 | Pride
Protein stability Phosphorylation Human breast cancer Protein conformation 
TranscriptomicsEffect of probiotic Lactobacillus casei Zhang on liver gene expression of hypercholesterolemic rats
The hypocholesterolemic effect of probiotics has been observed, but the molecular mechanism of probiotic-host interaction is still obscure. In this study, DNA microarray technology was used to explore the gene expression profile of liver of hypercholesterolemic rats caused by administration of probi...
ORGANISM(S): Rattus norvegicus 
2011-12-31 | E-GEOD-23740 | biostudies-arrayexpress
ProteomicsHuman liver cell line LO2 LC-MS/MS
A hyperlipidaemia model of L02 cells was established using free fatty acids (FFA, oleate and palmitate, 2:1; Sigma-Aldrich, USA) at a final concentration of 1 mM for 24 h. Cells were allowed to attach overnight prior to HTG-medicated serum for 24 h and then exposed to FFA during drug treatment. Afte...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD045069 | Pride
Human Liver cell Lc-ms/ms 
UnknownThe Rice Cation/H+ Exchanger Family Involved in Cd Tolerance and Transport.
Not available
S-EPMC8348036 | biostudies-literature
UnknownAsymmetrical effects of deafness-associated mitochondrial DNA 7516delA mutation on the processing of RNAs in the H-strand and L-strand polycistronic transcripts.
Not available
S-EPMC7641755 | biostudies-literature
UnknownLi2CO3-affiliative mechanism for air-accessible interface engineering of garnet electrolyte via facile liquid metal painting.
Not available
S-EPMC7382479 | biostudies-literature
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