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ProteomicsVisualization and identification of bioorthogonally-labeled exosome proteins following systemic administration in mice - Figure 5
Exosomes transport biologically active cargo (e.g., proteins and microRNA) between cells, including many of the paracrine factors that mediate the beneficial effects associated with stem-cell therapy. Stem cell derived exosomes, in particular mesenchymal stem cells (MSCs), have been shown previously...
ORGANISM(S): Mus musculus (Mouse) 
2021-03-15 | PXD024484 | Pride
Cardiac ischemia Proteomics Exosomes Mice 
ProteomicsVisualization and identification of bioorthogonally-labeled exosome proteins following systemic administration in mice - Figure 6
Exosomes transport biologically active cargo (e.g., proteins and microRNA) between cells, including many of the paracrine factors that mediate the beneficial effects associated with stem-cell therapy. Stem cell derived exosomes, in particular mesenchymal stem cells (MSCs), have been shown previously...
ORGANISM(S): Mus musculus (Mouse) 
2021-03-15 | PXD024485 | Pride
Cardiac ischemia Proteomics Mouse Exosome 
ProteomicsVisualization and identification of bioorthogonally-labeled exosome proteins following systemic administration in mice - Figure 4B left panel
Exosomes transport biologically active cargo (e.g., proteins and microRNA) between cells, including many of the paracrine factors that mediate the beneficial effects associated with stem-cell therapy. Stem cell derived exosomes, in particular mesenchymal stem cells (MSCs), have been shown previously...
ORGANISM(S): Mus musculus (Mouse) 
2021-03-15 | PXD024483 | Pride
Cardiac ischemia Exosomes Proteomics Mice 
ProteomicsVisualization and identification of bioorthogonally-labeled exosome proteins following systemic administration in mice
Exosomes transport biologically active cargo (e.g., proteins and microRNA) between cells, including many of the paracrine factors that mediate the beneficial effects associated with stem-cell therapy. Stem cell derived exosomes, in particular mesenchymal stem cells (MSCs), have been shown previously...
ORGANISM(S): Mus musculus (Mouse) 
2021-03-15 | PXD024482 | Pride
Exosomes Proteomics Cardiac eschemia 
ProteomicsCell type-specific metabolic labelling of nascent proteomes in vivo
Changes in protein expression drive both the acute responses and long-lasting adaptation of cells to internal and external stimuli. While advances in labelling strategies have made it possible to examine general proteome dynamics, it is still not possible to access the proteomes of specific cell typ...
ORGANISM(S): Mus musculus (Mouse) 
2017-11-10 | PXD007703 | Pride
Anl Boncat Azidonorleucine Nascent proteomes Funcat Metabolic labeling 
UnknownVisualization and Identification of Bioorthogonally Labeled Exosome Proteins Following Systemic Administration in Mice.
Not available
S-EPMC8058422 | biostudies-literature
UnknownLight-Activatable, Cell-Type Specific Labeling of the Nascent Proteome.
Not available
S-EPMC11450754 | biostudies-literature
ProteomicsCell-specific crosstalk proteomics reveals cathepsin B signaling as a driver of glioblastoma malignancy near the subventricular zone
Glioblastoma (GBM) is the most prevalent and aggressive malignant primary brain tumor. GBM proximal to the lateral ventricles (LVs) is more aggressive, potentially due to subventricular zone (SVZ) contact. Despite this, crosstalk between GBM and neural stem/progenitor cells (NSC/NPCs) is not well un...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2024-06-24 | PXD044773 | Pride
Metrs l274g Glioma Proteomics Lateral ventricle Stem cell niche Subventricular zone Brain cancer Neurogenesis Click chemistry Senescence 
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