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TranscriptomicsSeasonal RNAseq of Antarctic krill, Euphausia superba, from three different latitudinal regions of the Southern Ocean
The experiment aimed to investigate seasonal and regional differences in gene expression in Antarctic krill in three different latitudinal regions of the Southern Ocean with variable photoperiodic conditions: South Georgia (54°S), South Orkneys/Bransfield Strait (60°S-63°S) and Lazarev Sea (62°S -66...
ORGANISM(S): Euphausia superba 
2020-08-12 | E-MTAB-7467 | biostudies-arrayexpress
ProteomicsCD22 interactome
CD22 (Siglec-2) is a member of the Siglec family. It is an inhibitory co-receptor of the B-cell-receptor (BCR) and inhibits B–cell activation. Upon BCR stimulation ITIMs in the cytoplasmic tail of CD22 are phosphorylated. This triggers CD22 signalling pathways, which lead to a decreased calcium mobi...
ORGANISM(S): Gallus gallus (Chicken) 
2020-05-06 | PXD013801 | Pride
Cullin 3 Silac B cells Cd22 Qexactive plus Dt40 cells 
ProteomicsQuantitative phosphoproteomics analysis of olfactory receptor signaling in prostate cancer cells
The olfactory receptor PSGR1 is not only expressed in olfactory tissue but shows expression in the prostate. In addition, the expression of this receptor is elevated in prostate cancer as well as other prostate diseases and can be used as diagnostic marker. The signalling cascade triggered by the ac...
ORGANISM(S): Homo sapiens (Human) 
2016-07-08 | PXD000985 | Pride
Nhe1 Prostate cancer Pyk2 Psgr1 Ionone Phosphoproteomics 
ProteomicsCombinatorial native MS and LC-MS/MS approach reveals high intrinsic phosphorylation of human Tau
Abnormal changes in the neuronal microtubule-associated protein Tau, such as high phosphorylation and aggregation, are considered hallmarks of cognitive deficits in Alzheimer disease. Abnormal phosphorylation is thought to take place before aggregation, and therefore it is often assumed that phospho...
ORGANISM(S): Spodoptera frugiperda Homo sapiens (Human) Escherichia coli 
2020-11-20 | PXD020985 | Pride
Alzheimer disease Native mass spectrometry Tau protein Phosphorylation Liquid chromatography-mass spectrometry 
ProteomicsFecal detection of calprotectin subunits links IBD activity with chronicity of intestinal inflammation.
Quantification of the human S100A8/S100A9 tetrameric protein complex in stool, referred to as fecal calprotectin, is an extensively validated biomarker supporting the diagnosis and management of gastrointestinal diseases1,2. The quaternary protein structures (called configuration here) of S100A8 and...
ORGANISM(S): Homo sapiens (Human) 
2025-12-18 | PXD068250 | Pride
Calprotectin  s100a8  s100a9  inflammatory bowel diseases  gut  crohn's disease  ulcerative colitis  adaptive immunity  inflammation  biomarker  nlrp1  inflammasome 
ModelsMetabolic model of Sulfolobus solfataricus
Metabolic model of Sulfolobus solfataricus
2017-04-24 | 231 | FAIRDOMHub
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