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ProteomicsNeprilysins regulate muscle contraction and heart function via cleavage of SERCA-inhibitory micropeptides
Muscle contraction depends on strictly controlled Ca2+ transients within myocytes. A major player maintaining these transients is the sarcoplasmic/endoplasmic reticulum Ca2+ ATPase, SERCA. Activity of SERCA is regulated by binding of micropeptides and impaired expression or function of these peptide...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2022-06-01 | PXD027738 | Pride
Neprilysin Calcium homeostasis Metallopeptidase Micropeptides Serca Heart physiology Drosophila melanogaster 
GenomicsPanax ginseng cultivar:C.A. Meyer
Panax ginseng cultivar:C.A. Meyer Transcriptome or Gene expression
PRJNA266260 | ENA
TranscriptomicsHost cell tropism of Propionibacterium acnes: infection scenarios differ on skin and prostate epithelia
Proprionibacterium acnes is a Gram positive bacterium found ubiquitously on human skin, where it is typically considered to assume a commensal relationship with its host. However, it is also closely associated with the skin condition acne vulgaris. More controversially, it has a postulated involveme...
ORGANISM(S): Homo sapiens 
2012-11-21 | E-GEOD-33731 | biostudies-arrayexpress
ProteomicsCopper impairs hepatic selenoprotein P release
Selenoprotein P is a hepatokine which is essential for maintaining systemic selenium homeostasis and is used as serum biomarker for the selenium status in humans. In addition to selenium, also copper homeostasis is mainly regulated by the liver coordinating systemic distribution of copper bound to c...
ORGANISM(S): Homo sapiens (Human) 
2023-07-20 | PXD036300 | Pride
Selenoprotein p Wilson’s disease Selenium Copper Secretome 
ProteomicsProteomic investigation of Peristenus spretus ovary
Peristenus spretus (Hymenoptera: Braconidae) is one of the important nymph endoparasitoids for biological control of green mired bug, Apolygus lucorum Meyer-Dür (Heteroptera: Miridae). However, knowledge on the genetic regulation of P. spretus reproduction is very limited. Here, the proteomic approa...
ORGANISM(S): Peristenus Sp. 
2019-06-11 | PXD014219 |
TranscriptomicsPropionibacterium acnes as a frequent inflammatory agent involved in prostate cancer
Prostate cancer is the second leading cause of male cancer deaths in the United States and Europe. Current evidence implicates an inflammatory mechanism as a cause of prostate carcinogenesis. Here we show that the bacterium Propionibacterium acnes (P. acnes) is prevalent in prostate glandular tissue...
ORGANISM(S): Homo sapiens 
2010-12-22 | E-GEOD-18109 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of wildtype or Hyp (X-linked hypophosphatemic) mouse kidney after feeding control or low phosphate diet to study changes in gene expression in response to low-phosphate diet.
This is a study of the change in gene expression in mouse kidney after feeding control (1.0% P) or low phosphate diet (0.03% P) for 3 or 5 days to normal or Hyp (X-linked hypophosphatemic) mice at 5 weeks of age. The mice were C57BL/6J. Normal wild-type mice, hemizygous Hyp (Hyp/Y) male mice, or h...
ORGANISM(S): Mus musculus 
2007-12-13 | E-GEOD-868 | biostudies-arrayexpress
UnknownDesymmetrizing Heteroleptic [Cu(P^P)(N^N)][PF6] Compounds: Effects on Structural and Photophysical Properties, and Solution Dynamic Behavior.
Not available
S-EPMC7796056 | biostudies-literature
TranscriptomicsRNA-seq study of major P.aeruginosa PA14 transcription factors
Gene regulation via transcription factors influences the metabolic, adaptive and pathogenic capabilities of the organism. We report the transcriptomes of the mutants of six major P. aeruginosa PA14 trancription factors - RhlR, LasR, Anr, GacA, FleQ and CbrB. The P. aeruginosa PA14 transposon mutants...
ORGANISM(S): Pseudomonas aeruginosa 
2016-03-01 | E-GEOD-55328 | biostudies-arrayexpress
UnknownPhospho-specific plasma p-tau181 assay detects clinical as well as asymptomatic Alzheimer's disease.
Not available
S-EPMC9082389 | biostudies-literature
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