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Human dendritic cells were unexposed or exposed to the microfilaria of B. malayi for 48hrs. The cells were washed, protein extracted, processed and analyzed by mass spectrometry.
ORGANISM(S): Homo sapiens (Human) Brugia malayi 
2016-07-12 | PXD004522 | Pride
We have previously shown that the microfilarial (mf) stage of Brugia malayi can inhibit the mammalian target of rapamycin (mTOR; a conserved serine/threonine kinase critical for immune regulation and cellular growth) in human dendritic cells (DC) and we have proposed that this mTOR inhibition is ass...
ORGANISM(S): Brugia malayi 
2021-01-12 | PXD021844 | Pride
Loiasis, caused by the filarial nematode Loa loa, imposes a significant burden of disease in endemic regions in West and Central Africa. Manifestations include microfilaria in the blood (MF) and migration of the adult eye worm (EW), with clinical presentations ranging from asymptomatic infections to...
ORGANISM(S): Homo sapiens (Human) 
2025-07-04 | PXD057547 | Pride
Loiasis, caused by the filarial nematode Loa loa, imposes a significant burden of disease in endemic regions in West and Central Africa. Manifestations include microfilaria in the blood (MF) and migration of the adult eye worm (EW), with clinical presentations ranging from asymptomatic infections to...
ORGANISM(S): Homo sapiens (Human) 
2025-07-14 | PXD063487 | Pride
Loa loa isolate:DRC Genome sequencing
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