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MetabolomicsLION-web validation lipidomics experiments (FA-incorporation, membrane fluidty)
A major challenge for lipidomic analyses is the handling of the large amounts of data and the translation of results to interpret the involvement of lipids in biological systems. We built a new lipid ontology (LION) that associates over 50,000 lipid species to biophysical, chemical and cell biologic...
2019-04-24 | MTBLS757 | MetaboLights
ProteomicsSimple Strategy of Integrating the Micro-centrifugation-based Extraction and 4-Hexylphenylazosulfonate for the Preparation of Plant Microsomal Proteins for Bottom-Up Proteomics
The preparation of high-quality microsomal proteins (MPs) is of critical importance to high-throughput microsomal proteomics. The isolation of MPs for proteomic analysis has to date relied on Ultracentrifugation-based methods (UBMs), however, these methods are labor-intensive, time-consuming, and un...
ORGANISM(S): Oryza sativa subsp. japonica (Rice) 
2021-09-29 | PXD025132 | Pride
Rice leaves Perseus Label-free quantitative proteomics Ultracentrifugation Micro-centrifugation Azo Maxquant Microsomal membrane extraction Plasma membrane Sds 
UnknownAn Integrated Approach for the Efficient Extraction and Solubilization of Rice Microsomal Membrane Proteins for High-Throughput Proteomics.
Not available
S-EPMC8460067 | biostudies-literature
ProteomicsRegulation of the microsomal proteome by salicylic acid and deficiency of phosphatidylinositol‐4‐kinases β1 and β2 in Arabidopsis thaliana
Phosphatidylinositol-4-kinases β1 and β2 (PI4Kβ1/PI4Kβ2), which are responsible for phosphorylation of phosphoinositol to phosphatidylinositol-4-phosphate, have an important role in vesicular trafficking in plants. Moreover, PI4Kβ1/PI4β2 negatively regulate biosynthesis of phytohormone salicylic aci...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2021-02-24 | PXD019737 | Pride
Arabidopsis thaliana Microsomal fraction Phosphatidylinositol-4-kinases β1 and β2 Salicylic acid Label-free quantification Lc-ms/ms 
ProteomicsMembrane proteome of L. amazonensis PH8 and LV79 strains
Leishmaniasis is a serious disease caused by several species of protozoa from Leishmania genus. Parasite molecules that contribute to survival in the insect and vertebrate host are named virulence factors. We have recently shown that L. amazonensis PH8 and LV79 strains have different infectivity in ...
ORGANISM(S): Leishmania amazonensis 
2022-08-10 | PXD017870 | Pride
Virulence Gp63 Leishmania amazonensis strains Membrane proteome 
TranscriptomicsExpression data from human amnion mesenchymal cells treated with interleukin-1-beta for 1hr and 8hr
Premature birth continues to be a challenging pregnancy complication, and a body of literature indicates that inflammation can contribute to premature delivery by converting a receptive uterine environment to a hostile one. Cytokines have been demonstrated to provoke up-regulation of inflammatory g...
ORGANISM(S): Homo sapiens 
2011-06-02 | E-GEOD-26315 | biostudies-arrayexpress
ProteomicsQuantitative proteome analysis reveals changes of membrane proteins in Sedum plumbizincicola under cadmium stress
Sedum plumbizincicola is an herbaceous species tolerant of excessive cadmium accumulation in above-ground tissues. The implications of membrane proteins, especially integrative membrane proteins such as transporters, in Cd detoxification in plants have received attention in recent years, but a compr...
ORGANISM(S): Sedum plumbizincicola 
2021-12-30 | PXD025302 | Pride
Cadmium stress Tmt labeling Membrane proteome Sedum plumbizincicola 
UnknownImportance of membrane structural integrity for RPE65 retinoid isomerization activity.
Not available
S-EPMC2843217 | biostudies-literature
TranscriptomicsTranscription profiling of human intestinal mucosa after exposure to Lactobacillus plantarum WCFS1
the human in vivo transcriptional response of small intestinal mucosa to Lactobacillus plantarum
ORGANISM(S): Homo sapiens 
2008-10-17 | E-MEXP-1328 | biostudies-arrayexpress
TranscriptomicsFunctional expression of membrane alanyl-aminopeptidase (CD13/APN) promotes tumor cell proliferation and neoangiogenesis in malignant gliomas.
Malignant gliomas are characterized by marked neovascularization and increased tumor cell proliferation. Recently, membrane alanyl-aminopeptidase (CD13/APN) has been identified to play a crucial role in neoangiogenesis. In this study, we show that among various central nervous system tumors, maligna...
ORGANISM(S): Homo sapiens 
2012-05-27 | E-GEOD-37923 | biostudies-arrayexpress
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