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ProteomicsFebrile Infant Diagnostic Assessment and Outcome Olink Dataset
The FIDO (Febrile Infant Diagnostic assessment and Outcome) study aimed to look at different diagnostic approaches to identify infants with a fever at low and high-risk of serious infection. FIDO was a multicentre prospective observational cohort study that enrolled infants ≤90 days of age presentin...
ORGANISM(S): Homo sapiens (Human) 
2026-05-29 | PAD000035 | Pride
Blood biomarkers Infant Infection Meningitis 
ProteomicsRoasted English Walnut Label-Free LC-MS/MS Quantification
Thermal processing of allergenic foods has the potential to induce a number of changes in the constituent allergens, but many of the effects of heat treatment are poorly defined. Like numerous other commonly allergenic tree nuts, walnuts often undergo heat treatment, such as roasting, prior to consu...
ORGANISM(S): Juglans regia (English walnut) 
2016-05-18 | PXD000907 | Pride
Food allergens Walnut Thermal processing 
ProteomicsThe fate of bioaccessible coeliac toxic motifs and IgE epitopes during simulated gastro-intestinal digestion of pizza base
Understanding how food processing may modify allergen bioaccessibility and the evolution of immunologically active peptides in the gastrointestinal tract is essential if knowledge-based ap-proaches to reducing the allergenicity of food is to be realised. A soy-enriched wheat-based pizza base was sub...
ORGANISM(S): Glycine max Triticum aestivum (Wheat) 
2022-08-12 | PXD031067 | Pride
Allergen In vitro digestion Ige epitope Allergenicity risk assessment. Coeliac toxic motif Wheat Soy Gluten Mass spectrome-try 
ProteomicsBile Salts Enhance the Susceptibility of the Allergenic Lipid Transfer Protein from Peach, Pru p 3 to in vitro gastrointestinal digestion
Sensitisation to the lipid transfer protein Pru p 3 is associated with severe allergic reactions to peach, the proteins stability being thought to play a role in its allergenicity. Lipid binding increases susceptibility of Pru p 3 to digestion and so the impact of bile salts on the in vitro gastroin...
ORGANISM(S): Prunus persica 
2023-10-24 | PXD037801 | Pride
Disulphide bonds Immunoactivity Digestibility Bile salts Pru p 3 
ProteomicsLow Molecular Weight Allergens from English Walnut (Juglans Regia)
Low molecular weight (LMW) proteins were purified from English walnuts (J. regia cv. Chandler). The LMW proteins were separated by anion exchange chromatography. The anion exchange fractions were analyzed by SDS-PAGE, and protein bands were excised. In gel trypsin digestion was conducted (following ...
ORGANISM(S): Juglans regia (English walnut) 
2019-11-28 | PXD000634 | Pride
Food allergen Tree nut Vicilin Walnut 
ProteomicsRelative quantitation of coeliac toxic motifs and IgE epitopes in cereals containing gluten using proteomic profiling
Cereals-based foods cause immune-mediated adverse reactions including coeliac disease and IgE-mediated allergies. Proteomic profiling of proteins carrying coeliac toxic motifs and allergens has been undertaken in wheat, barley, rye and oats in order to understand whether some cereal species, such as...
ORGANISM(S): Triticum aestivum (Wheat) Hordeum vulgare (Barley) Secale cereale Avena sativa 
2026-02-23 | PXD039539 | Pride
Coeliac disease Proteomic profiling Gluten 
ProteomicsBiomarker identification in hospitalised patients with COVID-19: a cohort study of acute infection and convalescence.
Pilot bottom-up depleted proteomic analysis of patients from the ManARTS COVID-19 cohort in early stages of the pandemic, for method development of high-throughput proteomics using small volumes of plasma and a 15-minute gradient. Demonstrates proof-of-concept for stratifying patients in an opportun...
ORGANISM(S): Homo sapiens (Human) 
2026-06-08 | PXD061500 | Pride
Human Lc-ims-ms Plasma Covid-19 
MetabolomicsSingle cell lipidomics of adherent gut epithelial cell lines Caco2 and HT29-MTX reveals a metabolic switch

Raw MS data files for the CaCo02 and HT29-MTX single cells isolated using the Yokogawa SS2000 for the research article 'Single cell lipidomics of adherent gut epithelial cell lines Caco2 and HT29-MTX reveals a metabolic switch' 

2026-03-18 | MTBLS14074 | MetaboLights
UnknownImpact of the Covid-19 pandemic on neuropsychiatric symptoms and antipsychotic prescribing for people with dementia in nursing home settings.
Not available
S-EPMC10286750 | biostudies-literature
MetabolomicsMass Spectrometry Imaging of Lipids in a Gut Epithelial Cell Model

Scope: The Caco2/HT29-MTX co-culture system is widely used as a cell model of the intestinal epithelium. Although the gut epithelium plays an important role in the uptake of free fatty acids and the resynthesis of triglycerides, the lipid distribution profile of the two-dimensional co-culture sys...

2025-06-14 | MTBLS12599 | MetaboLights
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