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MetabolomicsMulti-Omics Unveils Strain-Specific Neuroactive Metabolite Production Linked to Inflammation Modulation by Bacteroides and Their Vesicles

18 Bacteroidetes isoaltes were analyzed for their neuroactive potentail using un-targeted and targeted metabolomics. The bacteria were grown to stationary phase, the supernatant was separated and purified using 0.22 um filter. The metabolome from the supernatant was extracted using standard Metha...

2025-08-12 | MTBLS10526 | MetaboLights
ProteomicsThree Diverse Granule Preparation Methods for Proteomic Analysis of Mature Rice (Oryza sativa L.) Starch Grain
Starch is the primary form of reserve carbohydrate storage in plants. Rice (Oryza sativa L.) is a monocot whose reserve starch is organized into compounded structures within the amyloplast, rather than a simple starch grain (SG). The mechanism governing the assembly of the compound SG from polyhedra...
ORGANISM(S): Oryza sativa (Rice) 
2022-06-09 | PXD032314 | Pride
Starch grain (sg) Amyloplast Starch granule-associated protein (sgap) Septum-like structure (sls) Rice Starch granule Plastoskeleton 
ProteomicsProteomic Analysis of Rana sylvatica Reveals Differentially Expressed Proteins in Liver in Response to Anoxia, Dehydration or Freezing Stress
Ectothermic animals that live in seasonally cold regions are adapted to seasonal variation and specific environmental conditions. During the winter, some amphibians hibernate terrestrially and encounter a limited amount of environmental water, deficient oxygen, and extremely low temperatures that ca...
ORGANISM(S): Lithobates sylvaticus 
2024-08-10 | PXD050540 | Pride
Lc-ms Proteomics 
ProteomicsPrenatal low-dose MeHg exposure leads to proteomic and transcriptomic alterations consistent with neurodegenerative disease in the cerebellum of C57BL/6 mice
Methylmercury (MeHg) is a global pollutant that readily crosses the blood–brain barrier and placenta, posing significant risks to fetal neurodevelopment. While the cerebellum is a recognized target of MeHg toxicity in adults, the mechanisms underlying fetal exposure remain poorly defined. In this st...
ORGANISM(S): Mus musculus (Mouse) 
2026-02-06 | PXD068503 | Pride
Proteomics Mehg Prenatal Disease latency Cerebellum Transcriptomics Neurodegenerative disease 
ProteomicsComprehensive characterization of raw and processed quinoa from conventional and organic farming by label-free shotgun proteomics
Quinoa is widely recognized for its exceptional nutritional properties, particularly its complete protein content. This study, for the first time, investigates the effects of processing methods (boiling and extrusion) and farming conditions (conventional and organic) on the quinoa’s proteomic profil...
ORGANISM(S): Chenopodium quinoa 
2025-01-17 | PXD050043 | Pride
Raw quinoa Nanolc-ms/ms Processed quinoa Shotgun proteomics Conventional farming Organic farming 
MetabolomicsMulti-level analysis of gut microbiome extracellular vesicles-host interaction reveals a connection to gut-brain axis signaling.

Microbiota-released extracellular vesicles (MEVs) have emerged as a key player in intercellular signaling. However, their involvement in the gut-brain axis has been poorly investigated. In this study, we aimed to investigate the cargo capacity of MEVs for bioactive metabolites and their interacti...

2025-08-12 | MTBLS8494 | MetaboLights
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