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ProteomicsIn vivo proximity-labeling with miniTurboID to screen for protein-protein interactions in the filamentous ascomycete Sordaria macrospora
The Biotin Identification (BioID) method is an in vivo labeling strategy for the identification of cellular microenvironments in animal cells, plants, yeast and filamentous fungi. With this method, the protein of interest (POI) is fused to a promiscuous biotin ligase. The ligase biotinylates proxima...
ORGANISM(S): Sordaria macrospora 
2025-05-12 | PXD061752 | Pride
Sordaria macrospora Stripak Proximity labeling Miniturbo Miniturboid Bioid 
ProteomicsProximal interaction network of ARF GTPases
The Arf GTPase family is involved in a wide range of cellular regulation including membrane trafficking and organelle structure assembly. Here, we have generated a proximity interaction network for the Arf family using the miniTurboID approach combined with TMT-based quantitative mass spectrometry. ...
ORGANISM(S): Homo sapiens (Human) 
2022-07-20 | PXD033382 | Pride
Arf gtpases Tmt Proximal labeling Ms 
ProteomicsIdentification of the bacteriophage nucleus protein interaction network
Here, we use proximity labeling and localization mapping to systematically identify proteins associated with the major nuclear shell protein chimallin (ChmA) and other distinctive structures assembled by these phages. We identify six uncharacterized nuclear shell-associated proteins, one of which di...
ORGANISM(S): Pseudomonas phage PhiPA3 
2024-01-26 | PXD041684 | Pride
Phage nucleus Miniturboid Phage 
UnknownIn vivo proximity-labeling with miniTurboID to screen for protein-protein interactions in the filamentous ascomycete Sordaria macrospora
Not available
S-EPMC12145721 | biostudies-literature
ProteomicsProximity interactomes of human PRICKLE1, PRICKLE2 and PRICKLE3
Prickle represents an evolutionarily conserved family of proteins that is specifically linked to Wnt/planar cell polarity (PCP) signalling. This signalling pathway is crucial for the correct polarization of epithelial cells along the plane of the epithelial tissue in both Drosophila and vertebrates....
ORGANISM(S): Homo sapiens (Human) 
2026-02-09 | PXD057854 | Pride
Hek293 t-rex Wnt/planar cell polarity (pcp) signalling Prickle Miniturboid 
ProteomicsProximity interactome of lymphatic VE-cadherin reveals mechanisms of junctional remodeling and reelin secretion.
In this study, we are the first to use the MiniTurboID generation of the proximity-dependent biotin identification (BioID) technology to illuminate how the lymphatic endothelial cell (LEC) VE-cadherin interactome changes during junctional remodeling in response to the lymphangiocrine factor adrenome...
ORGANISM(S): Homo sapiens (Human) 
2024-09-05 | PXD040452 | Pride
Ve-cadherin Exocyst Lymphatic endothelial cells Adherens junctions Reelin Bioid 
UnknownDefining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.
Not available
S-EPMC9433938 | biostudies-literature
ProteomicsProbing kinase proximity interactome modulation upon drug treatment by miniTurboID proximity labelling
In a systematic effort to profile kinase inhibitors, which also act as degraders, we identified multiple hit compounds. These were subjected to detailed mechanism of action elucidation including analysis of the perturbed interactome and its effect on degradation. For our first example, LYN, Src inhi...
ORGANISM(S): Homo sapiens (Human) 
2025-09-04 | PXD062184 | Pride
Kinase inhibitors Tmt 
UnknownPRICKLE3 protects VANGL proteins from CK1-mediated phosphorylation and RNF43-mediated degradation.
Not available
S-EPMC12859043 | biostudies-literature
UnknownThe ubiquitin E3 ligase ARIH1 regulates hnRNP E1 protein stability, EMT and breast cancer progression.
Not available
S-EPMC8933277 | biostudies-literature
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