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ProteomicsGlycation modulates glutamatergic signaling and exacerbates Parkinson’s disease-like phenotypes
Alpha-synuclein (aSyn) is a central player in the pathogenesis of synucleinopathies due to its accumulation in typical protein aggregates in the brain. However, it is still unclear how it contributes to neurodegeneration. Type-2 diabetes mellitus is a risk factor for Parkinson’s disease (PD) ...
ORGANISM(S): Mus musculus (Mouse) 
2022-05-20 | PXD032832 | Pride
Brain Parkinson's disease Glycation 
ProteomicsGlycoAvatars: Bead-Coated Membrane Models for Studying the Cancer-Immune Cells Interactome
Immature O-glycosylation, characterized by the Tn antigen expression rather than complex glycans, is prevalent in advanced solid tumors and promotes immune evasion. We developed GlycoAvatars, magnetic beads coated with plasma-membrane glycoproteins from glycoengineered cancer cell models, to identif...
ORGANISM(S): Homo sapiens (Human) 
2026-09-07 | PXD060750 | Pride
UnknownActive Low-Density Polyethylene-Based Films by Incorporating α-Tocopherol in the Free State and Loaded in PLA Nanoparticles: A Comparative Study.
Not available
S-EPMC10855272 | biostudies-literature
UnknownUnderstanding the Inguinal Sinus in Sheep (Ovis aries)-Morphology, Secretion, and Expression of Progesterone, Estrogens, and Prolactin Receptors.
Not available
S-EPMC5536006 | biostudies-literature
UnknownG-Quadruplex Aptamer-Ligand Characterization.
Not available
S-EPMC9609330 | biostudies-literature
ProteomicsCharacterization of CD44s glycoproteoforms in bladder tumours and bladder cancer cell culture models
Bladder cancer (BC) is a major health concern retaining high mortality rates when diagnosed at advanced stages. In this context, the clinical management of BC requires the introduction of new biomarkers and molecular targets capable to elicit precision medicine therapeutical approaches. A promising ...
ORGANISM(S): Homo sapiens (Human) 
2022-05-19 | PXD028307 | Pride
Glycosylation Cd44 Glycoproteogenomics Bladder cancer Alternative splicing 
UnknownEstimating population sizes to evaluate progress in conservation of endangered golden lion tamarins (Leontopithecus rosalia).
Not available
S-EPMC6550383 | biostudies-literature
UnknownDesign, synthesis, antinociceptive and anti-inflammatory activities of novel piroxicam analogues.
Not available
S-EPMC6268254 | biostudies-literature
TranscriptomicsNeuroligin-associated microRNA-932 targets actin and regulates memory
Increasing evidence suggests microRNAs (miRNAs) control levels of mRNA expression during development of the nervous system and during sensory elicited remodelling of the brain. We used an associative olfactory learning paradigm (proboscis extension response) in the honeybee Apis mellifera to detect ...
ORGANISM(S): Apis mellifera 
2014-02-01 | E-GEOD-51795 | biostudies-arrayexpress
UnknownInvestigation of Coagulation Biomarkers to Assess Clinical Deterioration in SARS-CoV-2 Infection.
Not available
S-EPMC8211892 | biostudies-literature
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