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UnknownFluorinated triphenylphosphonium analogs improve cell selectivity and in vivo detection of mito-metformin.
Not available
S-EPMC9768319 | biostudies-literature
TranscriptomicsRIP: miR-202 mimic-transfected HeLa cells vs. negative control
Potential miR-202 targets were identified using a targetome-wide RIP-based microarray. HeLa cells were transfected with either a miR-202 mimic or a scrambled single-stranded RNA negative control. RNA was isolated from total cell lysate prior to IP and from antibody-immobilized Protein G agarose be...
ORGANISM(S): Homo sapiens 
2012-12-19 | E-GEOD-42981 | biostudies-arrayexpress
UnknownMitochondria control functional CaV1.2 expression in smooth muscle cells of cerebral arteries.
Not available
S-EPMC3050675 | biostudies-literature
ProteomicsSIRT3 interactions and mitochondrial proteome during HCMV infection
SIRT3 has been shown to inhibit HCMV infection, but the mechanism under the antiviral effect is not clear. To identify the mediator of SIRT3 antiviral function, we aim to identify and quantify SIRT3 interactions during HCMV infection. A set of large-scale IPs were performed to determine the specific...
ORGANISM(S): Homo sapiens (Human) 
2021-04-01 | PXD018995 | Pride
Hcmv Mitochondrial proteome Ip-ms Sirt3 
ProteomicsFinding the LC3-interactors in senescent human A549 cells during influenza A virus infection
To screen age-related regulators of mitophagy, we examined LC3-interacting proteins by proximity-dependent biotin identification. LC3B was cloned into a mammalian expression vector tagged with a mitochondrial OMM-targeted APEX2 (mito-APEX) label for proximity-based identification of LC3-interacting ...
ORGANISM(S): Homo sapiens (Human) 
2025-09-29 | PXD057110 | Pride
Influenza a virus Lc3 Ifection Senescent human cells 
ProteomicsCo-Immunoprecipitation of TMEM65
Mitochondrial Ca2+ transport is a critical process in cellular physiology. One pathway for export occurs via Na+/Ca2+exchange (mito-NCX) machinery. TMEM65 has recently been shown to be crucial for mito-NCX activity, but its precise mechanistic role remains unknown. To evaluate whether TMEM65 forms a...
ORGANISM(S): Homo sapiens (Human) 
2026-02-09 | PXD064897 | Pride
Co-ip Lc-ms/ms 
GenomicsTunneling nanotubes mediate mitochondrial homeostasis in cancer
Tunneling nanotubes mediate mitochondrial homeostasis in cancer
PRJEB94402 | ENA
ProteomicsInsights into the role of VPS39 and its interaction with CP204L and A137R in ASFV infection
The African swine fever virus (ASFV) is a large and complex DNA virus that causes a highly le-thal disease in swine, for which no antiviral drugs or vaccines are currently available. Studying viral–host protein-protein interactions advances our understanding of the molecular mecha-nisms underlying v...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2024-09-17 | PXD054169 | Pride
African swine fever virus  protein-protein interaction  virus-host interaction 
ProteomicsIdentification of proteins interacting with GPAT4 in HUVECs cell line.
The endocardium plays a pivotal role in governing myocardial development, and understanding the intrinsic regulatory insights will help apprehend pathological cardiomyopathy. Glycerol-3-phosphate acyltransferase 4 (GPAT4) is an endoplasmic reticulum (ER) membrane anchored protein. While the role of ...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD061136 | Pride
Gpat4 Er stress Huvecs 
UnknownThymidine Kinase 1 Drives Skin Cutaneous Melanoma Malignant Progression and Metabolic Reprogramming.
Not available
S-EPMC8927676 | biostudies-literature
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