Sort   by:  
 Page size 
ProteomicsMitotic post-translational modifications of histones promote chromatin compaction in vitro
As histones undergo major changes in their post-translational modifications during mitotic entry, we speculated that the spectrum of cell cycle-specific histone modifications might contribute to chromosome compaction during mitosis. To test this hypothesis, we isolated core histones from interphase ...
ORGANISM(S): Gallus gallus (Chicken) 
2018-10-24 | PXD007116 | Pride
Ptms Chromatin condensation Histones Mitotic histones 
GenomicsInterrogating histone acetylation and BRD4 as mitotic bookmarks of transcription [Histones]
Interrogating histone acetylation and BRD4 as mitotic bookmarks of transcription [Histones]
PRJNA526633 | ENA
UnknownMitotic post-translational modifications of histones promote chromatin compaction in vitro.
Not available
S-EPMC5627050 | biostudies-literature
GenomicsGenome-wide distribution of histones modifications in mouse ESC Rif1+/+ and Rif1-/-
Analyzed histones modifications: H3K9 H3K4 H3K27 H4K20
ORGANISM(S): Mus musculus 
2015-12-24 | E-MTAB-3743 | biostudies-arrayexpress
ProteomicsPreferential phosphorylation on old histones during early mitosis in human cells
How histone posttranslational modifications (PTMs) are inherited through cell cycle remains poorly understood. Canonical histones are made in the S phase of cell cycle. Combining mass spectrometry-based technologies and stable isotope labeling by amino acids in cell culture (SILAC), we interrogate t...
ORGANISM(S): Homo sapiens (Human) 
2016-06-01 | PXD003709 | Pride
Mass spectrometry Mitosis Histone modifications Cell cycle Histone phosphorylation 
ProteomicsA time-resolved atlas of histone modifications during mitotic entry
Mitotic chromosome formation is essential for faithful chromosome segregation in metazoans. While condensin complexes are critical for the formation of rod-shaped mitotic chromosomes, additional mechanisms—particularly those involving phosphorylation and deacetylation of specific histone residues—ha...
ORGANISM(S): Gallus gallus (Chicken) 
2026-05-13 | PXD066101 | Pride
Chicken Ptms Mitosis Histones Lcms 
GenomicsInterrogating histone acetylation and BRD4 as mitotic bookmarks of transcription [Histones]
Global changes in chromatin organization and the cessation of transcription during mitosis are thought to challenge the resumption of appropriate transcription patterns following mitosis. The acetyl-lysine binding protein BRD4 has been previously suggested to function as a transcriptional “bookmark”...
ORGANISM(S): Mus musculus 
2019-04-10 | GSE128161 | GEO
ProteomicsAnalysis of barley chromosomal proteome: a multiapproach exploration of flow cytometry-sorted mitotic chromosomes
Proteins contribute to the structure of chromatin and regulate its functions. The basic building block of chromatin in eukaryotes is the nucleosome containing histones. Structural maintenance of chromosomes complexes perform the assembly of genomic DNA into the higher organizational structures of in...
ORGANISM(S): Hordeum vulgare (Barley) 
2021-07-21 | PXD024689 | Pride
Prediction Proteomics Mass spectrometry Flow cytometry Barley Chromatin Chromosome 
ProteomicsMassive histone H3 phosphorylation without mitotic chromosome condensation
Histone post-translation modifications change dramatically as cells enter mitosis, Indeed, histone phosphorylation and deacetylation have been proposed to be major factors driving the compaction of mitotic chromosomes. However, whether these modification changes directly regulate mitotic chromatin c...
ORGANISM(S): Gallus gallus (Chicken) 
2026-09-22 | PXD078615 | Pride
Cell cycle Mitotic-like chromosomes Premature chromosome condensation Histone modifications 
ProteomicsQuantification of parental and new histones H3, H4 and H2A by mass spectrometry: analysis of their dynamics along cell cycle progression in WT and MCM2-2A mutant mouse ESCs
During DNA replication parental, nucleosomic histones are segregated almost symmetrically to the two daughter DNA strands enabling mitotic inheritance of histones and their PTMs. In MCM2 histone-binding mutant ESCs (MCM2-2A), histones are recycled asymmetrically to the leading strand. To evaluate if...
ORGANISM(S): Mus musculus (Mouse) 
2023-08-30 | PXD030364 | Pride
Histone Mouse Ms Silac Pulse-silac Esc Mcm2 
Sort   by:  
 Page size