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In this study, merging in silico transcriptomic data and in situ TMA studies, we first highlighted the clinical significance and the value as prognostic factors of the embryonic TFs TWIST1 and TWIST2, thus linking their level of expression with the outcome of NB patients. Secondly, using NB cells k...
ORGANISM(S): Homo sapiens (Human) 
2022-01-10 | PXD024200 | Pride
Title of Publication: Histone Deacetylase 7 Regulates Cell Survival and TCR Signaling in CD4/CD8 Double-Positive Thymocytes Abstract of publicaton: CD4/CD8 double-positive (DP) thymocytes express the transcriptional repressor Histone Deacetylase 7 (HDAC7), a class IIa HDAC that is exported from the ...
ORGANISM(S): Mus musculus 
Neuroblastoma cell lines genetically modified to overexpress Anaplastic lymphoma kinase (ALK) point mutations or the ALK wild-type isoform were injected subcutaneously or orthotopically into NOD-SCID-gamma or athymic Swiss nude mice, respectively. After development of the tumor, RNA was extracted fr...
ORGANISM(S): Mus musculus 
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