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ProteomicsCharacterization of I-Ab MHCII immunopeptidome eluted from control and obese (Ob/Ob) mice (2)
In Dendritic cells (DC), the MHC II eluted immunopeptidome reflects the antigenic composition of the microenvironment. Proteins are transported and processed into peptides in endosomal MHC II compartments through autophagy or phagocytosis; extracellular peptides can also directly bind MHC II protein...
ORGANISM(S): Mus musculus (Mouse) 
2021-03-21 | PXD018783 | Pride
Mouse i-ab mhcii peptidome  lc/ms/ms dda on qe mass spectrometer 
ProteomicsNano LC-MS/MS DDA mass spectrometry profiling of I-Ab MHCII immunopeptidome eluted from B6 mice on normal and high fructose/high fat (HFHF) diet
In Dendritic cells (DC), the MHC II eluted immunopeptidome reflects the antigenic composition of the microenvironment. Proteins are transported and processed into peptides in endosomal MHC II compartments through autophagy or phagocytosis; extracellular peptides can also directly bind MHC II protein...
ORGANISM(S): Mus musculus (Mouse) 
2022-08-22 | PXD026068 | Pride
Mouse i-ab immunopeptidome  dda nanolc-ms/ms  orbitrap fusion tribrid mass spectrometer 
ProteomicsCharacterization of I-Ab MHCII immunopeptidome eluted from control and obese (Ob/Ob) mice using a combination of data-dependent (DDA) and data-independent acquisition (DIA) nanoLC mass spectrometry
In Dendritic cells (DC), the MHC II eluted immunopeptidome reflects the antigenic composition of the microenvironment. Proteins are transported and processed into peptides in endosomal MHC II compartments through autophagy or phagocytosis; extracellular peptides can also directly bind MHC II protein...
ORGANISM(S): Mus musculus (Mouse) 
2021-03-21 | PXD023581 | Pride
Mouse dendritic cells  i-ab mhc-ii immunopeptidome  dda and dia nanolcms 
ProteomicsA tissue-based draft map of the murine MHC class I immunopeptidome
The array of peptides presented to CD8+ T cells by major histocompatibility complex (MHC) class I molecules is referred to as the MHC class I immunopeptidome. Although the MHC class I immunopeptidome is ubiquitous in mammals and represents a critical component of the adaptive immune system, very lit...
ORGANISM(S): Mus musculus (Mouse) 
2018-06-19 | PXD008733 | Pride
Tissue Mass spectrometry Mhc Immunopeptidome Map 
ProteomicsMouse thymic, splenic B cells and splenic DC immunopeptidome
C57BL/6 Mouse: I-Ab immunopeptidome presented by thymus, splenic B cells and splenic DCs. Human lymphoblastoid cells: HLA-DR immunopeptidome identified from different cell dilutions. Splenic B cells Files- B cells 1 (121616WTII), B cells 2 (072417MHCII-1), B cells 3(072417MHCII-2) Thymus Files-Thym...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2021-03-10 | MSV000087031 | MassIVE
ProteomicsLabel-free quantitative data dependent (DDA) and independent (DIA) analysis of the I-Ab-MHCII peptidomes eluted from cervical and mesenteric dendritic cells (DCs) of B6 mice.
In Dendritic cells (DC), the MHC II eluted immunopeptidome reflects the antigenic composition of the microenvironment. Proteins are transported and processed into peptides in endosomal MHC II compartments through autophagy or phagocytosis; extracellular peptides can also directly bind MHC II protein...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2024-05-14 | MSV000094761 | MassIVE
UnknownDistinguishing Signal From Noise in Immunopeptidome Studies of Limiting-Abundance Biological Samples: Peptides Presented by I-Ab in C57BL/6 Mouse Thymus.
Not available
S-EPMC8116589 | biostudies-literature
ProteomicsImmunepeptidome of Coxsackievirus B3 infection models of human enterocyte and antigen presenting cell lines
Coxsackieviruses B (CVBs) emerge as candidate environmental triggers for the autoimmunity against pancreatic islet β cells leading to type 1 diabetes. Persistent CVB infections in the gut and pancreas correlate with islet autoantibody seroconversion, suggesting defective antiviral control in predisp...
ORGANISM(S): Homo sapiens (Human) 
2026-05-07 | PXD070471 | Pride
Coxsackievirus b Autoimmunity Human leukocyte antigen (hla) Immunopeptidomics Intestinal immunity Type 1 diabetes 
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