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ProteomicsDeletion of the transcription factors Hsf1, Msn2 and Msn4 in yeast uncovers transcriptional reprogramming in response to proteotoxic stress
The heat shock response is an ancient and ubiquitous program allowing organisms to survive adverse environmental conditions. In S. cerevisiae, three transcription factors, Hsf1, Msn2 and Msn4, are thought to regulate the stress response. While Msn2/4 can be deleted, Hsf1 is essential. By combining t...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2024-01-31 | PXD024352 | Pride
Hsf1 Msn4 Msn2 Heat shock response 
TranscriptomicsThe role of the protein kinase-A pathway in the response to alkaline pH stress in yeast
Exposure of Saccharomyces cerevisiae to alkaline pH represents a stress condition that generates a compensatory reaction. Here we examine a possible role of the protein kinase-A (PKA) pathway in this response. The phenotypic analysis reveals that mutations that activate the PKA pathway (ira1 ira2, b...
ORGANISM(S): Saccharomyces cerevisiae 
2011-07-15 | E-GEOD-27925 | biostudies-arrayexpress
TranscriptomicsSaccharomyces cerevisiae cells: W303-1A vs W303-1A delta MSN2, MSN4
Transcriptional profiling of Saccharomyces cerevisiae cells comparing the W303-1A wildtype with the W303-1A double mutant for MSN2 and MSN4 during zinc deficient conditions Keywords: Genetic modification with zinc limitation
ORGANISM(S): Saccharomyces cerevisiae 
2008-12-23 | GSE11878 | GEO
TranscriptomicsThe yeast PP2A-CDC55 phosphatase regulates the transcriptional response to hyperosmolarity stress by regulating Msn2 and Msn4 [Time course 2]
The yeast PP2A-Cdc55 Serine/Threonine phosphatase regulates transcription under certain conditions. It is required for full activation of the environmental stress response mediated by the transcription factors Msn2 and Msn4. PP2A-Cdc55 contributes to sustained nuclear accumulation of Msn2 and Msn4 a...
ORGANISM(S): Saccharomyces cerevisiae Saccharomyces cerevisiae W303 
2012-11-06 | GSE42033 | GEO
TranscriptomicsThe yeast PP2A-CDC55 phosphatase regulates the transcriptional response to hyperosmolarity stress by regulating Msn2 and Msn4 [Time course 1]
The yeast PP2A-Cdc55 Serine/Threonine phosphatase regulates transcription under certain conditions. It is required for full activation of the environmental stress response mediated by the transcription factors Msn2 and Msn4. PP2A-Cdc55 contributes to sustained nuclear accumulation of Msn2 and Msn4 a...
ORGANISM(S): Saccharomyces cerevisiae 
2012-06-08 | GSE38565 | GEO
UnknownYeast protein phosphatase 2A-Cdc55 regulates the transcriptional response to hyperosmolarity stress by regulating Msn2 and Msn4 chromatin recruitment.
Not available
S-EPMC3623084 | biostudies-literature
UnknownStress-response transcription factors Msn2 and Msn4 couple TORC2-Ypk1 signaling and mitochondrial respiration to ATG8 gene expression and autophagy.
Not available
S-EPMC5788474 | biostudies-literature
TranscriptomicsSaccharomyces cerevisiae cells: W303-1A vs W303-1A delta MSN2, MSN4
Transcriptional profiling of Saccharomyces cerevisiae cells comparing the W303-1A wildtype with the W303-1A double mutant for MSN2 and MSN4 during zinc deficient conditions Keywords: Genetic modification with zinc limitation Two condition experiment, W303-1A vs W303-1A delta MSN2, MSN4. Biological ...
ORGANISM(S): Saccharomyces cerevisiae 
2008-12-22 | E-GEOD-11878 | biostudies-arrayexpress
TranscriptomicsThe yeast PP2A-CDC55 phosphatase regulates the transcriptional response to hyperosmolarity stress by regulating Msn2 and Msn4
The yeast PP2A-Cdc55 Serine/Threonine phosphatase regulates transcription under certain conditions. It is required for full activation of the environmental stress response mediated by the transcription factors Msn2 and Msn4. PP2A-Cdc55 contributes to sustained nuclear accumulation of Msn2 and Msn4 a...
ORGANISM(S): Saccharomyces cerevisiae 
2012-06-07 | E-GEOD-38565 | biostudies-arrayexpress
TranscriptomicsThe yeast PP2A-CDC55 phosphatase regulates the transcriptional response to hyperosmolarity stress by regulating Msn2 and Msn4
This SuperSeries is composed of the following subset Series: GSE38565: The yeast PP2A-CDC55 phosphatase regulates the transcriptional response to hyperosmolarity stress by regulating Msn2 and Msn4 [Time course 1] GSE42033: The yeast PP2A-CDC55 phosphatase regulates the transcriptional response to hy...
ORGANISM(S): Saccharomyces cerevisiae 
2012-11-06 | E-GEOD-42034 | biostudies-arrayexpress
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