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TranscriptomicsMSN2-mCherry vs. msn2 microarray
Transcriptional profiling of Msn2 regulated genes. Both strains are PKAas (TPK1M164G TPK2M147G TPK3M165G) and msn4-delta. One strain has Msn2 C-terminally tagged with mCherry and the other strain is msn2-delta. In this experiment, both strains were exposed to 3 uM 1-NM-PP1, which leads to Msn2 nucle...
ORGANISM(S): Saccharomyces cerevisiae 
2013-10-12 | E-MTAB-1945 | biostudies-arrayexpress
GenomicsMsn2-mediated nucleosome remodeling dynamics
Msn2-mediated nucleosome remodeling dynamics
PRJEB4737 | ENA
TranscriptomicsTranscription factor Msn2 dependent gene expression in two entomopathogen fungi, Beauveria bassiana and Metarhizium robertsii under thermal and oxidaitve stresses
Transcription factor Msn2 played crucial roles in mediating fungal stress tolerance, a determinant to the biocontrol potential of fungal entomopathogens. We characterized for the first time the functions of Beauveria bassiana Msn2 (BbMsn2) and Metarhizium robertsii (MrMsn2) by analyzing multi-phenot...
ORGANISM(S): Metarhizium robertsii 
2015-02-01 | E-GEOD-40765 | biostudies-arrayexpress
ProteomicsDeletion of the transcription factors Hsf1, Msn2 and Msn4 in yeast uncovers transcriptional reprogramming in response to proteotoxic stress
The heat shock response is an ancient and ubiquitous program allowing organisms to survive adverse environmental conditions. In S. cerevisiae, three transcription factors, Hsf1, Msn2 and Msn4, are thought to regulate the stress response. While Msn2/4 can be deleted, Hsf1 is essential. By combining t...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2024-01-31 | PXD024352 | Pride
Hsf1 Msn4 Msn2 Heat shock response 
TranscriptomicsMsn2 controls the yeast metabolic focus
Msn2 is a transcription factor required for integration of environmental and metabolic signals. Msn2 is directly regulated by the carbon source sensing PKA and AMP pathways. Here we analyse the role of Msn2 for metabolic adjustment by using point mutants mimicking the dephosphorylated state.
ORGANISM(S): Saccharomyces cerevisiae 
2016-10-08 | GSE81890 | GEO
TranscriptomicsThe role of the protein kinase-A pathway in the response to alkaline pH stress in yeast
Exposure of Saccharomyces cerevisiae to alkaline pH represents a stress condition that generates a compensatory reaction. Here we examine a possible role of the protein kinase-A (PKA) pathway in this response. The phenotypic analysis reveals that mutations that activate the PKA pathway (ira1 ira2, b...
ORGANISM(S): Saccharomyces cerevisiae 
2011-07-15 | E-GEOD-27925 | biostudies-arrayexpress
UnknownYeast transcription factor Msn2 binds to G4 DNA.
Not available
S-EPMC10570036 | biostudies-literature
UnknownStochastic modelling of nucleocytoplasmic oscillations of the transcription factor Msn2 in yeast.
Not available
S-EPMC2706453 | biostudies-literature
GenomicsMsn2-mediated nucleosome remodeling dynamics
The aim of this experiment was to determine, using MNAse-Seq, how nucleosomes get remodeled during an Msn2 activation timecourse genome-wide. Diploid strain EY2807/ASH79 with genotype TPK1M164G TPK2M147G TPK3M165G msn4::TRP1/LEU2 MSN2-mCherry NHP6a-iRFP::kanMX was used. This strain is PKAas, so upon...
ORGANISM(S): Saccharomyces cerevisiae 
2013-10-12 | E-MTAB-1950 | biostudies-arrayexpress
Transcriptomicsmsn2/4 mutant 3 hour exposure to zymolyase
We did transcription profiling on the effect of msn2 msn4 deletion, genes involved in several stress process Keywords: cell wall stress response S. cerevisiae (msn2/4 mutant) was grown on YEPD. For Zymolyase experiments, yeast cells were grown overnight at 24 °C to an optical density 0.8 - 1 (A600)...
ORGANISM(S): Saccharomyces cerevisiae 
2010-06-19 | E-GEOD-9934 | biostudies-arrayexpress
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