Sort   by:  
 Page size 
UnknownPhase III randomized trial of induction chemotherapy in patients with N2 or N3 locally advanced head and neck cancer.
Not available
S-EPMC4876357 | biostudies-literature
TranscriptomicsPhenobarbital mediates an epigenetic switch at the constitutive androstane receptor (CAR) target gene Cyp2b10 in the liver of B6C3F1 mice [MeDIP array].
Evidence suggests that epigenetic perturbations are involved in the adverse effects associated with some drugs and toxicants, including certain classes of non-genotoxic carcinogens. Such epigenetic changes (altered DNA methylation and covalent histone modifications) may take place at the earliest st...
ORGANISM(S): Mus musculus 
2011-12-16 | E-GEOD-34462 | biostudies-arrayexpress
TranscriptomicsPhenobarbital mediates an epigenetic switch at the constitutive androstane receptor (CAR) target gene Cyp2b10 in the liver of B6C3F1 mice [Expression array].
Evidence suggests that epigenetic perturbations are involved in the adverse effects associated with some drugs and toxicants, including certain classes of non-genotoxic carcinogens. Such epigenetic changes (altered DNA methylation and covalent histone modifications) may take place at the earliest st...
ORGANISM(S): Mus musculus 
2011-12-14 | E-GEOD-34423 | biostudies-arrayexpress
ProteomicsEZHIP / CXorf67 mimics K27M mutated oncohistones and functions as an intrinsic inhibitor of PRC2 function in aggressive posterior fossa ependymoma
Posterior fossa A (PFA) ependymomas comprise one out of nine molecular groups of ependymoma. PFA tumors are mainly diagnosed in infants and young children, show a poor prognosis and are characterized by a lack of the repressive histone H3 lysine 27 trimethylation (H3K27me3) mark. Recently, we report...
ORGANISM(S): Homo sapiens (Human) 
2019-07-08 | PXD012318 | Pride
Prc2 Ezhip Cxorf67 Ependymoma 
ProteomicsProteomics of tumor associated microglia, tumor tissue from SB28 glioblastoma mice, and control microglia
The 18 kDa translocator protein (TSPO) emerges as an important PET biomarker to assess the tumor microenvironment (TME) in glioblastoma. However, various cellular sources hamper interpretation and biological understanding of TSPO and other immune biomarkers in the TME. Thus, we established a novel m...
ORGANISM(S): Mus musculus (Mouse) 
2023-10-30 | PXD044033 | Pride
Tumor tissue Microglia Tumor associated microglia Sb28 glioblastoma 
Metabolomicsms-mint: Targeted metabolomics with Python

Metabolomics has emerged as a mainstream approach for investigating the complex metabolic underpinnings of living systems. Over recent years, metabolomics has increasingly been applied to large cohort studies that tax the limits of existing computational tools. Though effective when applied ...

2025-05-21 | MTBLS6696 | MetaboLights
UnknownEfficient shear wave elastography using transient acoustic radiation force excitations and MR displacement encoding.
Not available
S-EPMC6414262 | biostudies-literature
MetabolomicsEpithelial-Cell-Derived Phospholipase A2 Group 1B Is an Endogenous Anthelmintic
Immunity to intestinal helminth infections has been well studied, but the mechanism of helminth killing prior to expulsion remains unclear. Here we identify epithelial-cell-derived phospholipase A2 group 1B (PLA2g1B) as a host-derived endogenous anthelmintic. PLA2g1B is elevated in resistant mice an...
2018-08-13 | MTBLS523 | MetaboLights
UnknownThe olfactory diary: Tracking awareness and consciousness of the sense of smell throughout the day.
Not available
S-EPMC11129550 | biostudies-literature
ProteomicsCSF and brain proteomics of Trem2-mKate2 KI/wt.APPSAA/SAA.hTfR KI/KI mice
Triggering receptor expressed on myeloid cells 2 (TREM2) is a central regulator of microglial activity and loss-of-function coding variants are major risk factors for late onset Alzheimer’s disease (LOAD). To better understand the molecular and functional changes associated with TREM2 signalling in ...
ORGANISM(S): Mus musculus (Mouse) 
2025-12-08 | PXD065438 | Pride
Alzheimer's disease Csf Mouse Brain Trem2 Antibody treatment 
Sort   by:  
 Page size