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Proteomicsp97/VCP promotes the recycling of endocytic cargo
The endocytic pathway is of central importance for eukaryotic cells, as it enables uptake of extracellular materials, membrane protein quality control and recycling, as well as modulation of receptor signaling. While the ATPase p97 (VCP, Cdc48) has been found to be involved in the fusion of early en...
ORGANISM(S): Homo sapiens (Human) 
2023-09-28 | PXD041169 | Pride
Myof Myoferlin Vcp Cdc48 P97 Rab11 
UnknownTargeting MYOF suppresses pancreatic ductal adenocarcinoma progression by inhibiting ILF3-LCN2 signaling through disrupting OTUB1-mediated deubiquitination of ILF3.
Not available
S-EPMC12145718 | biostudies-literature
UnknownE3 ligase TRIM8 suppresses lung cancer metastasis by targeting MYOF degradation through K48-linked polyubiquitination.
Not available
S-EPMC11814372 | biostudies-literature
GenomicsBulk transcriptomic analysis of normal, premalignant state and tumor mouse models of VAV1-MYOF gene fusion in Peripheral T-Cell Lymphoma
Bulk transcriptomic analysis of normal, premalignant state and tumor mouse models of VAV1-MYOF gene fusion in Peripheral T-Cell Lymphoma
PRJNA701570 | ENA
GenomicsTruncating variant in MYOF gene is associated with limb-girdle type muscular dystrophy and cardiomyopathy
Truncating variant in MYOF gene is associated with limb-girdle type muscular dystrophy and cardiomyopathy
PRJNA487792 | ENA
GenomicsSingle cell RNA-seq analysis of normal, premalignant state and tumor mouse models of VAV1-MYOF gene fusion in Peripheral T-Cell Lymphoma
Single cell RNA-seq analysis of normal, premalignant state and tumor mouse models of VAV1-MYOF gene fusion in Peripheral T-Cell Lymphoma
PRJNA701571 | ENA
TranscriptomicsSingle cell RNA-seq analysis of normal, premalignant state and tumor mouse models of VAV1-MYOF gene fusion in Peripheral T-Cell Lymphoma
The goal of this study is to identify transcriptomic effects of VAV1-MYOF expression in mouse CD4+ T lymphocytes and tumor progression in TET2KO and TET2WT backgrounds. To this end, mice conditionally expressing VAV1-MYOF  were crossed with the CD4CreERT2 line  or CD4-Cre,  under the control of the ...
ORGANISM(S): Mus musculus 
2021-05-12 | GSE166672 | GEO
UnknownTruncating Variant in Myof Gene Is Associated With Limb-Girdle Type Muscular Dystrophy and Cardiomyopathy.
Not available
S-EPMC6607695 | biostudies-literature
TranscriptomicsBulk transcriptomic analysis of normal, premalignant state and tumor mouse models of VAV1-MYOF gene fusion in Peripheral T-Cell Lymphoma
The goal of this study is to identify transcriptomic effects of VAV1-MYOF expression in mouse CD4+ T lymphocytes in tumor development as well as changes in the microenvironment. To this end, mice conditionally expressing VAV1-MYOF  were crossed with the CD4CreERT2 line  or CD4-Cre,  under the contro...
ORGANISM(S): Mus musculus 
2021-05-12 | GSE166671 | GEO
TranscriptomicsTruncating variant in MYOF gene is associated with limb-girdle type muscular dystrophy and cardiomyopathy
Even though genetic studies of individuals with neuromuscular diseases have uncovered the molecular background of many cardiac disorders such as cardiomyopathies and inherited arrhythmic syndromes, the genetic cause of a proportion of cardiomyopathies associated with neuromuscular phenotype still re...
ORGANISM(S): Homo sapiens 
2019-08-24 | GSE119027 | GEO
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