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ProteomicsPivotal role for S-nitrosylation of DNA methyltransferase in epigenetic regulation
DNMTs catalyze the methylation of cytosine with SAM. DNA methylation affects key cellular processes by regulating gene expression, thus serving a variety of physiological and pathophysiological roles. However, the chemical mechanisms of DNA methylation by which its enzymatic activity is regulated ha...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD039437 | Pride
No Cancer S-nitrosylation Dna methylation Epigenetics 
UnknownCryo-EM micrographs of the symmetric sheathed filament of the ΔflaA1/A2 mutant in Leptospira biflexa
Not available
EMPIAR-13159 | biostudies-other
UnknownCryo-EM micrographs of the symmetric sheathed filament of the ΔfcpB mutant in Leptospira biflexa
Not available
EMPIAR-13158 | biostudies-other
ProteomicsThe pivotal and universal role of BGLT3 lncRNA in fetal globin gene expression
A highly selective and non-genotoxic G9a inhibitor, RK-701 was discovered, which upregulated the mRNA level of γ-globin but not β-globin both in human erythroid cells and in mice. Using RK-701, we examined the induction of the fetal (γ-) globin protein in human erythroid cells; HUDEP-2 and human CD3...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD033536 | Pride
Hemoglobin subunit Cultured cell Lc-ms/ms 
TranscriptomicsAn analysis of genomic structural alteration in three human ES cell lines.
To elucidate frequencies of genomic structural alterations, we performed an analysis using a SNP genotyping array (Illumina HumanCytoSNP-12 v2.1 DNA Analysis BeadChip Kit) for three human ES cell lines, namely, SEES-1, SEES-2, and SEES-3. Samples were collected after 4 to 60 passages to detect struc...
ORGANISM(S): Homo sapiens 
2015-05-20 | E-GEOD-54576 | biostudies-arrayexpress
UnknownAsymmetric sheath coordination controls flagellar architecture and function in Leptospira spirochete
Not available
S-SCDT-10_1038-S44318-026-00731-1 | biostudies-other
TranscriptomicsWhole genome transcriptional profile of human tissues and cells
We performed tiling array experiments to examine whole genome expression in human tissues. We investigated tissue specificity and association between evolutionary sequence conservation and transcription. A total of 22 tissues (bone marrow, cerebellum, colon, cortex, fetal brain, heart, kidney, live...
ORGANISM(S): Homo sapiens 
2013-12-31 | E-GEOD-18490 | biostudies-arrayexpress
TranscriptomicsOligoarray analysis of semi-global gene expression in ripening Japanese pear fruit
A custom oligoarray of Japanese pear (Pyrus pyrifolia) based on 9,812 independent ESTs from different tissues (fruits at various growth stages, vegetative and flower tissues) was designed and used for comprehensive investigation of gene expression before and during ripening (105 to 147 days after fu...
ORGANISM(S): Pyrus pyrifolia 
2010-10-12 | E-GEOD-18682 | biostudies-arrayexpress
UnknownNational trends in the outcomes of subarachnoid haemorrhage and the prognostic influence of stroke centre capability in Japan: retrospective cohort study.
Not available
S-EPMC10111904 | biostudies-literature
UnknownMicroRNA-33 inhibition ameliorates muscular dystrophy by enhancing skeletal muscle regeneration
Not available
S-SCDT-10_1038-S44321-025-00273-9 | biostudies-other
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