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TranscriptomicsRadiotolerance of Rhodospirillum rubrum S1H
In the present study, the susceptibility of the purple pigmented photosynthetic alphaproteobacterium Rhodospirillum rubrum S1H to gamma irradiation was investigated and its molecular response was characterised by means of gene expression analysis. R. rubrum S1H appears to be about 4 times more sen...
ORGANISM(S): Rhodospirillum rubrum 
2015-11-10 | E-GEOD-23799 | biostudies-arrayexpress
TranscriptomicsA small basic protein from the brz operon is involved in regulation of bop transcription in Halobacterium salinarum
An inhibitory effect of novobiocin on bop transcription was reported for the NRC1 strain of Hbt. salinarum ([17] Yang and DasSarma, 1990, [18] Yang et al, 1996), but its influence in strain R1 has not beeen known yet. We were interested to see the genome wide influences of novobiocin on transcriptio...
ORGANISM(S): Halobacterium salinarum 
2012-01-01 | E-MEXP-3219 | biostudies-arrayexpress
UnknownALS mutant FUS proteins are recruited into stress granules in induced pluripotent stem cell-derived motoneurons.
Not available
S-EPMC4486861 | biostudies-literature
ProteomicsStructural mechanism for inhibition of PP2A-B56 and oncogenicity by CIP2A
Abstract The protein phosphatase 2A (PP2A) heterotrimer PP2A-B56 is a human tumor suppressor. However, the molecular mechanisms inhibiting PP2A-B56in cancer are poorly understood. Here, we report molecular level details and structural mechanism of PP2A-B56inhibition by an oncoprotein CIP2A. Upon di...
ORGANISM(S): Mus musculus (Mouse) 
2023-03-11 | PXD030297 | Pride
Ap-ms Protein phosphatase Mouse Oncogene Interactome 
ProteomicsA divergent cyclin/cyclin-dependent kinase complex controls the atypical replication of Plasmodium berghei during gametogony and parasite transmission.
Cell cycle transitions are generally triggered by variation in the activity of cyclin-dependent kinases (CDKs) bound to cyclins. Malaria-causing parasites have a life cycle with unique cell-division cycles, and a repertoire of divergent CDKs and cyclins of poorly understood function and interdepende...
ORGANISM(S): Plasmodium berghei ANKA 
2020-06-17 | PXD017622 | Pride
Malaria Parasite Cyclin Kinase Warwick-rtp Cyclin-dependent Plasmodium 
ProteomicsPeptidomic Analysis of Natural Substrates of the Promiscuous Angiotensin-Converting Enzyme
In the current study we exploit this technical advantage to maximize discovery of possible substrates and products of ACE present in plasma
ORGANISM(S): Mus musculus (Mouse) 
2022-03-02 | PXD009611 | Pride
Peptidomics 
ProteomicsThe bulk cell density as decisive parameter and simple method for mesendodermal patterning of human pluripotent stem cells
We showed that the relation of pluripotent stem cell count to culture volume influences cardiomyogenic differentiation by affecting the concentration of secreted proteins that function as paracrine factors
ORGANISM(S): Homo sapiens (Human) 
2018-10-17 | PXD004874 | Pride
Human Lc-msms Cardiomyocytes Secretome 
ProteomicsMetabolic shift underlies recovery in reversible infantile respiratory chain deficiency
Reversible infantile respiratory chain deficiency (RIRCD) is a rare mitochondrial myopathy leading to severe metabolic disturbances in infants, which recover spontaneously after 6 months of age. RIRCD is associated with the homoplasmic m.14674T>C mitochondrial DNA mutation, however only ~1/100 carri...
ORGANISM(S): Homo sapiens (Human) 
2020-10-13 | PXD020181 | Pride
Mitochondrial myopathy Digenic inheritance Reversible infantile respiratory chain deficiency Homoplasmic trna mutation 
ProteomicsThe Plethora of Angiotensin-Converting Enzyme Substrates in Mouse Plasma
Angiotensin converting enzyme (ACE) is known for converting inactive angiotensin I into the potent vasoconstrictor angiotensin II, playing a critical role in blood pressure regulation. However, there is evidence that the dicarboxypeptidase activity of ACE is also essential for other physiological pr...
ORGANISM(S): Mus musculus (Mouse) 
2019-11-12 | PXD010258 | Pride
Peptidomics 
UnknownTDP-43 real-time quaking induced conversion reaction optimization and detection of seeding activity in CSF of amyotrophic lateral sclerosis and frontotemporal dementia patients.
Not available
S-EPMC7566418 | biostudies-literature
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