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MetabolomicsMetabolomic profiling of primary mouse proximal tubule cells (mPTCs) derived from 24-week-old CTR and Atg7 PT-KO kidneys
To explore the role of ATG7 in the kidney PT, we crossed mice homozygous for floxed alleles of Atg7 with Ggt1-Cre mice expressing Cre recombinase under the rat Ggt1 (gamma-glutamyltransferase 1) gene promoter. This generated Atg7fl/fl; γGt1cre/cre mice (hereafter referred to as Atg7 PT-KO), in which...
2026-09-30 | MTBLS15857 | MetaboLights
ProteomicsProteomic analysis of isolated integrin-associated adhesion complexes in Trastuzumab -sensitive and -resistant BT474 cells
Peptide analysis by LC-MS/MS was performed using a nanoACQUITY™ (Waters) Ultra Performance Liquid Chromatography (UPLC) column, coupled to an LTQ-Orbitrap XL (Thermo Fisher) equipped with a nanoelectrospray source (Proxeon).
ORGANISM(S): Homo sapiens (Human) 
2024-11-03 | PXD055603 | Pride
Adhesion Breast cancer Trastuzmab Itgb6 Erbb2 Her2 Herceptin 
ProteomicsProteomic Analysis of isolated integrin-associated adhesion complexes in HER2-18 CELLS
Peptide analysis by LC-MS/MS was performed using a nanoACQUITY™ (Waters) Ultra Performance Liquid Chromatography (UPLC) column, coupled to an LTQ-Orbitrap XL (Thermo Fisher) equipped with a nanoelectrospray source (Proxeon).
ORGANISM(S): Homo sapiens (Human) 
2024-11-03 | PXD055405 | Pride
Trastuzumab Adhesion Breast cancer Receptor trafficking Itgb6 Erbb2 Her2 
ProteomicsProteomic Analysis of isolated integrin-associated adhesion complexes in BT474 cells
Peptide analysis by LC-MS/MS was performed using a nanoACQUITY™ (Waters) Ultra Performance Liquid Chromatography (UPLC) column, coupled to an LTQ-Orbitrap XL (Thermo Fisher) equipped with a nanoelectrospray source (Proxeon).
ORGANISM(S): Homo sapiens (Human) 
2024-11-03 | PXD055411 | Pride
Trastuzumab Adhesion Breast cancer Receptor trafficking Erbb2 Her2 
ProteomicsProteogenomics insights into the hemi-biotrophic pathogen, Phytophthora capsici
This study was designed to evaluate the proteome profiles of Phytophthora capsici. We have utilized a proteogenomics pipeline for identification of proteins from P. capsici.
ORGANISM(S): Phytophthora capsici LT1534 
2022-03-02 | PXD003952 | Pride
Nanoacquity uplc Lc-mse Piper nigrum Proteinlynx global server 
ProteomicsTranscriptomics – assisted proteome profiling of black pepper (Piper nigrum L.)
This study was designed to evaluate the proteome profiles of Piper nigrum when challenged with three different biotic stress. We have utilized a transcriptome-assisted protein identification pipeline coupled with a BLAST2GO annotation.
ORGANISM(S): Piper nigrum 
2022-03-02 | PXD004008 | Pride
Nanoacquity uplc Lc-mse Piper nigrum Proteinlynx global server 
ProteomicsNear complete quantitative proteomics for Yeast
In this study, we attempted to achieve to date the most comprehensive coverage of the yeast proteome during log-phase growth and in the K11R mutant ubiquitin yeast strain with a combination of (1) extensive gel molecular weight fractionation and use of either of two digestion enzymes to improve cove...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2019-08-26 | PXD001928 | Pride
Yeast High coverage Silac Proteome Lc-ms/ms 
ProteomicsProteomic analysis of serum samples of paracoccidioidomycosis patients with severe pulmonary sequel
Pulmonary sequelae (PS) in patients with chronic paracoccidioidomycosis (PCM) typically include pulmonary fibrosis and emphysema. Knowledge of the molecular pathways involved in PS of PCM is required for treatment and biomarker identification. This non-concurrent cohort study included 29 patients wi...
ORGANISM(S): Homo sapiens (Human) 
2021-08-26 | PXD026906 | Pride
Molecular analysis Pulmonary fibrosis Paracoccidioides brasiliensis 
ProteomicsROME BioID2 raw proteomics data from ROME KO manuscript
For proteomics, samples were heated for 10 min at 95 degrees. After cooling down to room temperature, 4 uL of 500 mM IAA in 5%SDS was added to a final concentration of 40 mM and incubated in the dark for 30 min. Undissolved matter was centrifuged for 8 min at 13,000 x g. The supernatant was saved an...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2026-01-30 | MSV000100665 | MassIVE
ProteomicsLongitudinal Serum Proteomics In a Mouse Model of Lethal Endotoxemia
A total of thirty-two samples mouse serum samples were analyzed in duplicate (64 total injections) using an LC-MS system comprised of a nanoAcquity LC instrument (Waters nanoAcquity UPLC system, Milford, MA) connected to an Orbitrap Fusion Lumos tribrid mass spectrometer (Thermo Fisher Scientific, S...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2019-10-04 | MSV000084416 | MassIVE
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