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ProteomicsNanoToxClass: Investigation of dose-dependent nanomaterial effects in alveolar macrophages
In this study, alveolar macrophages (cell line NR8383) were treated with three different doses of nanomaterials (SiO2_15_Amino, SiO2_15_Unmod, SiO2_7, SiO2_40, TiO2_NM105) for 24 h. The effects were investigated using untargeted proteomics.
ORGANISM(S): Rattus norvegicus (Rat) 
2021-09-29 | PXD020158 | Pride
Macrophages Nanomaterials Rat Tmt Nanotoxclass 
ProteomicsNanoToxClass: Investigation of dose-dependent nanomaterial effects after instillations with rats
In this study, rats were exposed to three different doses of nanomaterials (SiO2_15_Amino, SiO2_15_Unmod, SiO2_7, SiO2_40) using instillations. Effects on exposure and recovery groups were compared using untargeted proteomics.
ORGANISM(S): Rattus norvegicus (Rat) 
2021-09-29 | PXD020184 | Pride
Instillation Nanomaterials Rat Tmt Nanotoxclass 
ProteomicsNanoToxClass: Investigation of dose- and time-dependent nanomaterial effects in alveolar epithelial cells
In this study, alveolar epithelial cells (cell line RLE-6TN) were treated with three different doses of nanomaterials (SiO2_15_Amino, SiO2_15_Unmod, SiO2_7, SiO2_40, TiO2_NM105) for 6 h, 24 h, and 48 h, respectively. The effects were investigated using untargeted proteomics.
ORGANISM(S): Rattus norvegicus (Rat) 
2021-09-29 | PXD020289 | Pride
Nanomaterials Rat Tmt Nanotoxclass Epithelial cells 
ProteomicsNanoToxClass: Investigation of dose-dependent nanomaterial effects after short-term inhalation studies (STIS) with rats
In this study, rats were exposed to three different doses of nanomaterials (SiO2_7, TiO2_NM105) using short-term inhalations. Effects on exposure and recovery groups were compared using untargeted proteomics.
ORGANISM(S): Rattus norvegicus (Rat) 
2021-09-29 | PXD020178 | Pride
Nanomaterials Stis Rat Tmt Nanotoxclass 
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