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ProteomicsLC-MS/MS-based Proteomics Approach for the Identification of Candidate Serum Biomarkers in Patients with Narcolepsy Type 1
The study is based on the identification of serum protein biomarkers for NT 1. A total of 27 serum samples were collected (16 NT 1 and 11 controls), the altered expression levels of low-abundant proteins (DEPs) associated with narcolepsy type 1 was investigated by comparing the proteomes of the two ...
ORGANISM(S): Homo sapiens (Human) 
2023-05-10 | PXD038248 | Pride
Narcolepsy type 1 Lc-ms/ms And orexin/hypocretin. Differentially expressed proteins (deps) Acute phase response signaling Autoimmunity Pathophysiology Human leukocyte antigen 
ProteomicsCerebrospinal fluid proteomics in recent-onset Narcolepsy type 1 reveals activation of the complement system
Narcolepsy type 1 (NT1) is a rare, chronic and disabling neurological disease causing excessive daytime sleepiness and cataplexy. NT1 is characterized pathologically by an almost complete loss of neurons producing the orexin neuropeptides in the lateral hypothalamus. Genetic and environmental factor...
ORGANISM(S): Homo sapiens (Human) 
2023-04-06 | PXD041093 | Pride
Neuroimmunology Coagulation system Cerebrospinal fluid Complement system Immune response Narcolepsy type 1 Proteomics 
GenomicsGut microbiota heterogeneity is associated with Narcolepsy type 1
Gut microbiota heterogeneity is associated with Narcolepsy type 1
PRJEB38491 | ENA
UnknownNocturnal Sleep Dynamics Identify Narcolepsy Type 1.
Not available
S-EPMC4507733 | biostudies-literature
UnknownHPLC analysis of CSF hypocretin-1 in type 1 and 2 narcolepsy.
Not available
S-EPMC6346108 | biostudies-literature
GenomicsmRNA and T cell receptor sequencing of patients with Pandemrix-associated narcolepsy type 1
Increased risk of Narcolepsy type 1 (NT1) was reported among children and adolescents vaccinated with AS03-adjuvanted pandemic influenza A vaccine (H1N1; Pandemrix®). We hypothesized that viral T cell epitope(s) in Pandemrix mimicked self-epitope(s), and that recognition of these cross-reactive e...
EGAS00001004886 | EGA
UnknownImpaired histaminergic neurotransmission in children with narcolepsy type 1.
Not available
S-EPMC6488909 | biostudies-literature
UnknownCircadian Rest-Activity Rhythm in Pediatric Type 1 Narcolepsy.
Not available
S-EPMC4863212 | biostudies-literature
UnknownExploring the clinical features of narcolepsy type 1 versus narcolepsy type 2 from European Narcolepsy Network database with machine learning.
Not available
S-EPMC6045630 | biostudies-literature
UnknownImpaired sleep-dependent memory consolidation in pediatric narcolepsy type 1.
Not available
S-EPMC11807881 | biostudies-literature
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