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ProteomicsChemical and Random Additive Noise Elimination (CRANE) - case_study - multicenter_dataset
The effectiveness of the novel electrospray ionisation - liquid chromatography mass spectrometry (ESI-LC-MS) data de-noising technique, CRANE, is demonstrated by denoising the MS1 and all the MS2 windows of the multicentre, data-independent acquisi-tion (DIA) MS dataset from Navarro, et al. (2016).
ORGANISM(S): Homo sapiens (Human) Escherichia coli Saccharomyces cerevisiae (Baker's yeast) 
2021-07-26 | PXD020529 | Pride
Lc-msms Random noise Chemical noise Denoise Baseline noise Dia 
ProteomicsIn-depth serum proteomics of hospitalized COVID-19 patients and PCR-negative healthy controls with HiRIEF LC-MS/MS
We performed in-depth MS-based plasma-proteome profiling in 20 hospitalised patients with COVID-19 and 7 healthy controls (PCR- and sero-negative for SARS-CoV-2) by high-resolution isoelectric focusing (HiRIEF) coupled with liquid chromatography and mass-spectrometry (LC-MS/MS). The SARS‐CoV‐2 PCR‐c...
ORGANISM(S): Homo sapiens (Human) 
2023-09-01 | PXD037486 | Pride
Covid-19 Human Serum Plasma Sars-cov-2 Hirief Lc-ms/ms 
ProteomicsAging induces hepatic oxidative stress and nuclear proteomic remodelling in liver from Wistar ratAging induces hepatic oxidative stress and nuclear proteomic remodelling in liver from Wistar rats
Aging induces oxidative stress and proteome remodeling in the nucleus from liver in Wistar rats
ORGANISM(S): Rattus norvegicus (Rat) 
2022-02-17 | PXD027773 | Pride
Oxidative stress nuclear liver wistar rat lc-ms/ms 
ProteomicsIdentification of kinase activity in ischemic heart disease
We performed discovery proteomics and phosphoproteomics analysis of human heart tissue to identify possibly hyperactive pathways in ischemic heart disease.
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD024727 | Pride
Phosphoproteomics Map kinase activity Myeloid cell coagulation Ischemic heart disease 
ProteomicsIdentification of spidroin proteins in the silk glands of Nephila clavipes spiders
Glands were frozen at -80 ºC immediately after being retrieved and stored under this condition until initiating the proteomics analysis protocol. Glands were washed with cold PBS and immersed in 120 l of homogenization buffer (50 mM Tris-HCl, pH 6.8, 10 mM DTT, 4% (w/v) SDS). Glands were boiled for ...
ORGANISM(S): Trichonephila clavipes 
2022-12-07 | PXD023141 | Pride
Spider silk  proteomics  liquid chromatography-tandem mass spectrometry  silk gut 
ProteomicsEffects of chronic social stress on mitochondrial and mitochondrial-associated membrane protein networks in the mouse brain
Stressors challenge metabolic processes to adapt to ever-changing environmental conditions and herein, the brain is exceptionally amenable to change. Simultaneously, the high cerebral energy demands may render the brain particularly vulnerable to the metabolic consequences of psychological stress. M...
ORGANISM(S): Mus musculus (Mouse) 
2022-10-13 | PXD015983 | Pride
Mitochondrial-associated membrane Brain Mouse Chronic stress 
UnknownConnection of Isolated Stereoclusters by Combining 13C-RCSA, RDC, and J-Based Configurational Analyses and Structural Revision of a Tetraprenyltoluquinol Chromane Meroterpenoid from Sargassum muticum.
Not available
S-EPMC9319238 | biostudies-literature
UnknownDatasets for the validation of the "in vivo" siRNA-silencing of CD40 and for the detection of new markers of atherosclerosis progression in ApoE-deficient mice.
Not available
S-EPMC5128022 | biostudies-literature
ProteomicsProteome changes in retinal Mueller glial cells from a spontaneous equine model for autoimmune uveitis compared to healthy controls
Retinal Müller glial cells (RMG) play a central role in retinal neuroinflammation, actively participating in the immune response and adopting a dynamic inflammatory phenotype. However, the precise functions of RMG in retinal inflammation remain incompletely understood. In this study, we investigated...
ORGANISM(S): Equus caballus (Horse) 
2025-05-07 | PXD058170 | Pride
Quantitative label-free lc-ms/ms  retinal neuroinflammation  autoimmune uveitis  equine recurrent uveitis (eru)  spontaneous equine animal model  retinal mueller glial cells (rmg) 
UnknownClinical Assessment Specialists: A New Faculty Role to Improve Clerkship Assessment.
Not available
S-EPMC10940249 | biostudies-literature
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