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MetabolomicsThe lipid-metabolism enzyme ECI2 reduces neutrophil extracellular traps formation for colorectal cancer suppression
Abnormalities in ether lipid metabolism as well as the formation of neutrophil extracellular traps have recently been recognized as detrimental factors affecting tumorigenesis and progression. However, the role of abnormal ether lipid metabolism in colorectal cancer (CRC) evolution has not been repo...
2024-10-01 | MTBLS10323 | MetaboLights
MetabolomicsSpatial multi-omics inference of diabetes mellitus triggering pancreatic cancer growth through cholesterol-induced neutrophil extracellular traps

Spatial multi-omics inference of diabetes mellitus triggering pancreatic cancer growth through cholesterol-induced neutrophil extracellular traps

2025-11-26 | MTBLS12782 | MetaboLights
MetabolomicsHistidine improves Hashimoto thyroiditis by inhibiting the production of Neutrophil Txtracellular Traps

Objective: Metabolite abnormalities are potentially implicated in pathogenesis of Hashimoto’s thyroiditis (HT). An in-depth study of the relationship between HT and small molecule metabolites, as well as its pathogenesis, can help enhance the diagnosis, prognosis, and treatment of HT patients.

2025-10-12 | MTBLS12333 | MetaboLights
ProteomicsCharacterization of Early-Phase Neutrophil Extracellular Traps in Urinary Tract Infections
Neutrophils have an important role in rapid antimicrobial defenses against and resolution of urinary tract infections (UTIs). We show that a mechanism known as neutrophil extracellular trap (NET) formation is a strategy to combat pathogens in the urinary tract. Viscous aggregates that were present i...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-31 | MSV000080847 | MassIVE
MetabolomicsThe phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 inhibitor 3PO is a modulator of neutrophil metabolism, ROS production and NET release
Neutrophils are key effector leukocytes of the innate immune system and play a pivotal role in defending the host against microbial infections. Recent studies have identified a crucial link between glycolysis and neutrophil cellular functions. We have investigated in human neutrophils, the intricate...
2025-08-14 | MTBLS6215 | MetaboLights
ProteomicsSpecific post-translational histone mod. of neutrophil extracellular traps as immunogens & potential SLE Ab targets.
This SuperSeries is composed of the following subset Series: GSE32542: Murine serum reactivity to common autoantigens in response to immunization with neutrophil extracellular traps GSE32543: Human and murine serum reactivity to specific histone posttranslational modifications in neutrophil extracel...
ORGANISM(S): Homo sapiens 
2012-01-26 | E-GEOD-32544 | biostudies-arrayexpress
OtherNeutrophil Extracellular Traps in Ulcerative Colitis: A Proteome Analysis of Intestinal Biopsies.
Data from ProteomeXchange, PXD ID: PXD001608. File: UC_2_3.mzml. Ulcerative colitis sample. Published as part of Inflamm Bowel Dis. 2015 May 19 . From the Abstract: {{i}} The etiology of the inflammatory bowel diseases, including ulcerative colitis (UC), remains incompletely explained. We hypothesi...
ORGANISM(S): Homo_sapiens_viruses, Human, Bacteroides_thetaiotaomicron_vpi_5482, Escherichia_coli_k_12_substr__mg1655 
GPM32320015348 | GPMDB
Resource Reanalysis 
ProteomicsHuman and murine serum reactivity to specific histone posttranslational modifications in neutrophil extracellular traps
Introduction: Autoreactivity to histones is a pervasive feature of several human autoimmune disorders including systemic lupus erythematosus (SLE). Specific post-translational modifications (PTMs) of histones within neutrophil extracellular traps (NETs) may potentially drive the process by which to...
ORGANISM(S): Homo sapiens 
2012-01-26 | E-GEOD-32543 | biostudies-arrayexpress
ProteomicsProteomic analysis of neutrophil extracellular traps (healthy control, rheumatoid arthritis, systemic lupus erythematosus)_C4PR_LIV
Neutrophil Extracellular Traps (NETs) are chromatin-derived extracellular structures that are expelled from neutrophils in response to infectious or inflammatory stimuli. NET DNA structures are decorated with proteins including histones, myeloperoxidase and neutrophil elastase. NETs are implicated i...
ORGANISM(S): Homo sapiens (Human) 
2019-02-18 | PXD011796 | Pride
A23187 Neutrophil extracellular traps Pma Rheumatoid arthritis Systemic lupus erythematosus 
ProteomicsNETOME: The Molecular Characterization of Neutrophil Extracellular Traps (NETs)
Neutrophils are necessary in mamalian’s life and are the most abundant type of white blood cells in humans with biological roles relevant to inflammation and the entire host response. The release of neutrophil extracellular DNA in innate immune cells provides specific response to bacteria and fungi....
ORGANISM(S): Homo sapiens (Human) 
2022-10-25 | PXD016143 | Pride
Genomics Nets Neutrophils Extracellular dna Proteomics Netome 
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