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UnknownIn vitro induced regulatory T cells are unique from endogenous regulatory T cells and effective at suppressing late stages of ongoing autoimmunity.
Not available
S-EPMC4131893 | biostudies-literature
TranscriptomicsHypoxia-inducible factors enhance CD8+ T cell effector responses to persistent antigen.
Cytolytic activity by CD8+ cytotoxic T lymphocytes (CTL) is a powerful tactic in the elimination of intracellular pathogens and tumor cells. The destructive capacity of CTL is progressively dampened during chronic infection - yet the environmental cues and molecular pathways controlling immune “exha...
ORGANISM(S): Mus musculus 
2013-09-29 | E-GEOD-50158 | biostudies-arrayexpress
TranscriptomicsSingle cell RNA-seq of human CD8+ T cells binding the IAV HLA-A24/PB1 498-505 tetramer
PBMCs from 4 donors were stained with the influenza A virus HLA-A24/PB1 498-505 tetramer. Two donors (non-LIFT8 and non-LIFT12) showed TCR independent KIR binding to tetramers whereas the other two donors (Non-LIFT14 and Non-LIFT10) showed TCR specific binding. Cells were single-cell sorted on a BD ...
ORGANISM(S): Homo sapiens 
2021-04-08 | E-MTAB-10109 | biostudies-arrayexpress
UnknownLong-term sediment decline causes ongoing shrinkage of the Mekong megadelta, Vietnam.
Not available
S-EPMC7228934 | biostudies-literature
TranscriptomicsRNA-seq of mouse brain tissue repopulating microglia in response to traumatic brain injury
We assessed the roles of repopulating microglia in brain repair using mouse models. In this project, we show that removal of microglia from the mouse brain has little impact on the outcome of TBI but inducing the turnover of these cells through either pharmacologic or genetic approaches can yield a ...
ORGANISM(S): Mus musculus 
2020-02-15 | E-MTAB-8765 | biostudies-arrayexpress
TranscriptomicsExpression data from murine natural killer cell subsets based on Ly49 receptor expression in C57BL/6 mice (C/I+ versus Ly49G2+ NK cells)
Natural killer (NK) cells have differential expression of inhibitory and activating receptors. NK cells that express inhibitory receptors with high binding affinity to self are considered licensed and normally functional cells, while those with low affinity are unlicensed are considered hyporesponsi...
ORGANISM(S): Mus musculus 
2014-09-01 | E-GEOD-56662 | biostudies-arrayexpress
ProteomicsInfluenza-derived peptide presentation by HLA-A*24:02
Identification of influenza virus-derived peptides presented by Human Leukocyte Antigen (HLA) molecules of the C1R (Class I reduced) B-lymphoblastoid cell line, transfected with the HLA class I allele HLA-A*24:02, after influenza infection.
ORGANISM(S): Homo sapiens (Human) 
2021-04-08 | PXD020292 | Pride
Lc-msms Hla Influenza Immunopeptidome 
ProteomicsInfluenza-derived peptide presentation by HLA-A*11:01
Analysis of the immunopeptidome of Human Leukocyte Antigen (HLA)-A*11:01 during influenza infection. Analyses were performed using the Class I reduced C1R cell line transfected with the HLA class I allele HLA-A*11:01.
ORGANISM(S): Homo sapiens (Human) 
2022-02-15 | PXD028985 | Pride
Lc-msms Hla Influenza Immunopeptidome 
TranscriptomicsDevelopment and Validation of a Novel Molecular Biomarker Diagnostic Test for the Early Detection of Sepsis
Introduction: Sepsis is a complex immunological response to infection characterized by early hyperinflammation followed by severe and protracted immunosuppression, suggesting that a multi-marker approach has the greatest clinical utility for early detection, within a clinical environment focused on ...
ORGANISM(S): Homo sapiens 
2011-11-01 | E-GEOD-28750 | biostudies-arrayexpress
UnknownRheumatoid arthritis and older age are associated with lower humoral and cellular immune response to primary series COVID-19 mRNA vaccine.
Not available
S-EPMC11606055 | biostudies-literature
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