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Application of Systems Genetics analysis for systematic evaluation of candidate causal genes associated with risk of Type 1 Diabetes along with follow-up bioinformatics pathway analysis. Total RNA obtained from whole blood (for EBV-B cells) and Peripheral blood mononuclear cells (PBMCs) (for T-cells...
ORGANISM(S): Homo sapiens 
Potassium channels regulate membrane potential, calcium flux, cellular activation and effector functions of adaptive and innate immune cells. The voltage-activated Kv1.3 channel is an important regulator of T cell-mediated autoimmunity and microglia-mediated neuroinflammation. Kv1.3 channels, via pr...
ORGANISM(S): Homo sapiens (Human) 
2026-03-23 | PXD059644 | Pride
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