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ProteomicsInteractome analysis of C. elegans synapses by TurboID-based proximity labeling
Proximity labeling provides a powerful in vivo tool to characterize the proteome of subcellular structures and the interactome of specific proteins. Using the highly active biotin ligase TurboID, we optimize a proximity labeling protocol for C. elegans. We use this protocol to characterise the prote...
ORGANISM(S): Caenorhabditis elegans 
2021-09-15 | PXD027068 | Pride
Interactome caenorhabditis elegans turboid proximity proteomics biotin labeling 
ProteomicsGlyphosate_proteomics - Glyphosate does not substitute for glycine in proteins of actively dividing mammalian cells
This is a first analysis of potential direct or indirect effects of glyphosate on protein post-translational modification in mammalian cell culture, using TMT labelling to control for false discoveries. Potential effects on the global proteome were also investigated.
ORGANISM(S): Homo sapiens (Human) 
2019-08-29 | PXD013744 | Pride
Glyphosate glyoxylate glycine protein modification tmt 
ProteomicsCdk5r1_KO_TMT-10plex_brain_cell-autonomous_proteomics
Concerted radial migration of newly born cortical projection neurons, from their birthplace to their final target lamina, is a key step in the assembly of the cerebral cortex. The cellular and molecular mechanisms regulating radial neuronal migration in vivo are however still unclear, let alone the ...
ORGANISM(S): Mus musculus (Mouse) 
2024-05-22 | PXD023222 | Pride
Mus musculus Brain Facs sorted 
ProteomicsCullin 3 Mouse Brain TMT-based Proteomics Analysis
This project consists in 3 datasets: - Samples from adult mouse brains (Hippocampus, Cortex and Cerebellum): Cul3 +/- or +/+; 5 animals per condition. - Samples from embryonic mouse cortex: either Cul3 +/- or +/+ - Samples from embryonic mouse cortex: Cul3 fl/fl Emx-1-Cre ("hom"); Cul3 +/fl Emx1-Cre...
ORGANISM(S): Mus musculus (Mouse) 
2021-03-26 | PXD017040 | Pride
Mouse brain cullin 3 cul3 autism cortex cerebellum hippocampus embryonic adult tmt dda high ph rp 
ProteomicsShared behavioural impairments in visual perception and place avoidance across different autism models are driven by periaqueductal grey hypoexcitability in Setd5 haploinsufficient mice.
Despite the diverse genetic origins of autism spectrum disorders (ASDs), affected individuals share strikingly similar and correlated behavioural traits that include perceptual and sensory processing challenges. Notably, the severity of these sensory symptoms is often predictive of the expression of...
ORGANISM(S): Mus musculus (Mouse) 
2024-05-15 | PXD051022 | Pride
Setd5 Superior coliculus Sensorimotor transformation Periaqueductal grey 
ProteomicsPSME3 Regulates Migration and Differentiation of Myoblasts
This is the first of 2 proteomics experiments in the same project (see https://www.biorxiv.org/content/10.1101/2025.01.08.632048v1.full). This one is a co-Immunoprecipitation experiment aimed at determining the interaction partners of proteasome regulator PSME3. PSME3 was captured from C2C12 cell ly...
ORGANISM(S): Mus musculus (Mouse) 
2025-06-17 | PXD063339 | Pride
Psme3 C2c12 Differentiation Myogenesis Proteasome 
ProteomicsPSME3 Regulates Migration and Differentiation of Myoblasts
This is the second of two experiments in this project. It sought to measure the changes in the proteome following depletion of PSME3. C2C12 cells were depleted of PSME3 using specific siRNA. Controls received siRNA with a scrambled sequence. Cells were grown to confluency (Day 0 of differentiation),...
ORGANISM(S): Mus musculus (Mouse) 
2025-06-17 | PXD063351 | Pride
Psme3 C2c12 Differentiation Myogenesis Proteasome 
ProteomicsSingleWormProteomics
Proteome analysis at the single worm level
ORGANISM(S): Caenorhabditis Elegans (c. Elegans) 
2016-12-31 | PAe005596 | PeptideAtlas
ProteomicsGlobal phosphoproteomic profiling of TOW-dependent regulation of PIN phosphorylation
Auxin canalization is a self-organizing process that governs the flexible formation of vasculature by reinforcing the formation of auxin transport channels. A key prerequisite is the feedback between auxin signaling and directional auxin transport, mediated by PIN transporters. Despite the developme...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2026-03-31 | PXD070189 | Pride
Arabidopsis thaliana Tow Phosphorylation Root 
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