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ProteomicsGlycomic and Proteomic changes in aging brain nigrostriatal pathway
This study identifies the age related changes in glycan receptors of heparan sulfate (HS) proteoglycan (receptor for rAAV2), and/or N-glycans with terminal galactose (receptor for rAAV9) and proteomics for receptors and co-receptors of adeno-associated virus in the nigro-striatal region of the brain...
ORGANISM(S): Rattus norvegicus (Rat) 
2018-06-27 | PXD008990 | Pride
Hilic Mass spectrometry Reverse phase Gene therapy Aging nigro-striatal pathway Hilic-wax Lc-msms Label-free proteomics Heparan sulfate Adeno-associated virus N-glycans Proteomic Parkinson’s disease Glycomic 
UnknownA nigro-subthalamo-parabrachial pathway modulates pain-like behaviors.
Not available
S-EPMC9755217 | biostudies-literature
UnknownAge-dependent dopamine transporter dysfunction and Serine129 phospho-α-synuclein overload in G2019S LRRK2 mice.
Not available
S-EPMC5351259 | biostudies-literature
UnknownMultiple system atrophy-associated oligodendroglial protein p25α stimulates formation of novel α-synuclein strain with enhanced neurodegenerative potential.
Not available
S-EPMC8217051 | biostudies-literature
UnknownCombined deficiency of alpha and epsilon sarcoglycan disrupts the cardiac dystrophin complex.
Not available
S-EPMC3209833 | biostudies-literature
UnknownField Susceptibility of Almond (Prunus dulcis) Cultivars to Red Leaf Blotch Caused by Polystigma amygdalinum in Apulia (Italy) and Influence of Environmental Conditions.
Not available
S-EPMC12845356 | biostudies-literature
TranscriptomicsTranscriptome analysis in Dicer knock-out mice
The precise mechanisms by which microRNAs (miRNAs) contribute to the dynamic regulation of gene expression during forebrain development are still partly elusive. Here we show that depletion of miRNAs via genetic inactivation of Dicer after the onset of forebrain neurogenesis profoundly impairs the m...
ORGANISM(S): Mus musculus 
2012-11-14 | E-MTAB-1062 | biostudies-arrayexpress
UnknownRepurposing Simvastatin in Parkinson's Disease Model: Protection Is throughout Modulation of the Neuro-Inflammatory Response in the Substantia nigra.
Not available
S-EPMC10341642 | biostudies-literature
UnknownCholinergic system correlates of postural control changes in Parkinson's disease freezers.
Not available
S-EPMC10393403 | biostudies-literature
UnknownDistribution patterns of tau pathology in progressive supranuclear palsy.
Not available
S-EPMC7360645 | biostudies-literature
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