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ProteomicsProteome integral solubility alteration high-throughput proteomics assay identifies Collectin-12 as a non-apoptotic microglial caspase-3 substrate.
Caspases are a family of proteins mostly known for their role in the activation of the apoptotic pathway leading to cell death. In the last decade, caspases have been found to fulfil other tasks regulating the cell phenotype independently to cell death. Microglia are the immune cells of the brain re...
ORGANISM(S): Mus musculus (Mouse) 
2023-05-10 | PXD032835 | Pride
Caspase-3 Solubility Pisa Non-apoptotic Sustrates Colec12 Proteomics Microglia 
GenomicsAnti-apoptotic genes and non-coding RNAs are potential outcome predictors for ulcerative colitis
Anti-apoptotic genes and non-coding RNAs are potential outcome predictors for ulcerative colitis
PRJNA716331 | ENA
GenomicsSequencing Apoptotic DNA Breakpoints
DNA fragmentation is a well-recognized hallmark of apoptosis. However, the precise DNA sequences cleaved during apoptosis triggered by distinct mechanisms remain unclear. We used next-generation sequencing of DNA fragments generated in Actinomycin D-treated human HL-60 leukemic cells to generate a h...
ORGANISM(S): Homo sapiens 
2011-10-15 | E-GEOD-32997 | biostudies-arrayexpress
GenomicsInhibition of PRMT5 sensitizes B-cell non-Hodgkin lymphoma cells to both intrinsic and extrinsic apoptotic cell death
Inhibition of PRMT5 sensitizes B-cell non-Hodgkin lymphoma cells to both intrinsic and extrinsic apoptotic cell death
PRJNA1370848 | ENA
UnknownPlasma Membrane Localization of Apoptotic Caspases for Non-apoptotic Functions.
Not available
S-EPMC5972739 | biostudies-literature
UnknownApoptotic proteins with non-apoptotic activity: expression and function in cancer.
Not available
S-EPMC10071271 | biostudies-literature
Unknownp53 controls choice between apoptotic and non-apoptotic death following DNA damage.
Not available
S-EPMC9882237 | biostudies-literature
GenomicsNon-apoptotic caspase-8 is critical for orchestrating exaggerated inflammation during severe SARS-CoV-2 infection
Non-apoptotic caspase-8 is critical for orchestrating exaggerated inflammation during severe SARS-CoV-2 infection
PRJNA1188515 | ENA
ProteomicsDepletion of histone methyltransferase KMT9 inhibits lung cancer cell proliferation by inducing non-apoptotic cell death
Background: Lung cancer is the leading cause of cancer related death worldwide. Over the past 15 years no major improvement of survival rates could be accomplished. The recently discovered histone methyltransferase KMT9 as epigenetic regulator of prostate tumor growth has now raised hopes of enablin...
ORGANISM(S): Homo sapiens (Human) 
2020-05-26 | PXD014145 | Pride
Kmt9 Non-small cell lung cancer Proteomics Epigenetics Histone methyltransferase Lung cancer A549 Transcriptomics 
UnknownActivation of Pro-apoptotic Caspases in Non-apoptotic Cells During Odontogenesis and Related Osteogenesis.
Not available
S-EPMC5845891 | biostudies-literature
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