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ProteomicsNon-histone lysine methylation of grape berry
To gain a comprehensive understanding of non-histone methylation during grape berry ripening. A 4D-label free quantitative proteomics approach was used to study the non-histone methylation of lysine during grape berry development and ripening. The ‘Kyoho’ grape berries at EL 31, EL 33, EL 35 and EL ...
ORGANISM(S): Vitis Vinifera 
PXD042527 |
ProteomicsDissection of acetylomic profiles in T cell lymphoma following histone deacetylases inhibition
The aim was to dissect molecular changes in histone and non-histone protein acetylation dynamics following the genetic or pharmacological inhibition of HDAC activity in a model of Anaplastic Large Cell Lymphoma (ALCL), a T cell non-Hodgkin lymphoma, predominantly found in children and adolescents.
ORGANISM(S): Mus musculus (Mouse) 
2022-10-14 | PXD030503 | Pride
Acetylomics Histone deacetylase inhibitors Anaplastic large cell lymphoma Histone deacetylases Proteomics 
ProteomicsDepletion of histone methyltransferase KMT9 inhibits lung cancer cell proliferation by inducing non-apoptotic cell death
Background: Lung cancer is the leading cause of cancer related death worldwide. Over the past 15 years no major improvement of survival rates could be accomplished. The recently discovered histone methyltransferase KMT9 as epigenetic regulator of prostate tumor growth has now raised hopes of enablin...
ORGANISM(S): Homo sapiens (Human) 
2020-05-26 | PXD014145 | Pride
Kmt9 Non-small cell lung cancer Proteomics Epigenetics Histone methyltransferase Lung cancer A549 Transcriptomics 
GenomicsStage-specific dual function: EZH2 regulates human erythropoiesis by eliciting histone and non-histone methylation [ChIP-Seq]
Stage-specific dual function: EZH2 regulates human erythropoiesis by eliciting histone and non-histone methylation [ChIP-Seq]
PRJNA917631 | ENA
GenomicsHistone H1 non-autonomously promotes lipolysis in depressive Drosophila
Histone H1 non-autonomously promotes lipolysis in depressive Drosophila
PRJNA1204962 | ENA
ProteomicsA synthetic non-histone substrate to study substrate targeting by the Gcn5 HAT and sirtuin HDACs
Gcn5 and sirtuins are conserved HAT and HDAC enzymes that were first characterised as regulators of gene expression via histone acetylation. Although histone tails are important substrates of these enzymes, they also target non-histone proteins in diverse processes. Previously, we used SILAC-based m...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2019-02-25 | PXD012608 | Pride
Saga Gcn5 Consensus sequence Synthetic biology Acetylation Ada3 Sirtuin 
GenomicsStage-specific dual function: EZH2 regulates human erythropoiesis by eliciting histone and non-histone methylation [D7-EZH2-RNAseq]
Stage-specific dual function: EZH2 regulates human erythropoiesis by eliciting histone and non-histone methylation [D7-EZH2-RNAseq]
PRJNA918309 | ENA
GenomicsStage-specific dual function: EZH2 regulates human erythropoiesis by eliciting histone and non-histone methylation [D15-EZH2-RNAseq]
Stage-specific dual function: EZH2 regulates human erythropoiesis by eliciting histone and non-histone methylation [D15-EZH2-RNAseq]
PRJNA916879 | ENA
GenomicsHistone H1 regulates non-coding RNA turnover on chromatin in a m6A-dependent manner
Histone H1 regulates non-coding RNA turnover on chromatin in a m6A-dependent manner
PRJNA700879 | ENA
GenomicsProfiling of histone modification H3K27me3 in Norway spruce embryonic calli and non-embryonic calli
Profiling of histone modification H3K27me3 in Norway spruce embryonic calli and non-embryonic calli
PRJNA606776 | ENA
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