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TranscriptomicsTranscriptional regulation of the sialic acid utilization gene cluster of Bifidobacterium breve UCC2003 by a GntR-type transcriptional repressor.
Members of the genus Bifidobacterium are typically found in the gastrointestinal tract (GIT) of humans and other mammals. Bifidobacterium breve strains are numerically prevalent among the gut microbiota of healthy, breast-fed infants. The metabolism of sialic acid, a ubiquitous monosaccharide in the...
ORGANISM(S): Bifidobacterium breve UCC2003 
2015-03-05 | E-GEOD-62885 | biostudies-arrayexpress
TranscriptomicsMetabolism of four α-glycosidic linkage-containing oligosaccharides by Bifidobacterium breve UCC2003
Members of the genus Bifidobacterium are common inhabitants of the gastrointestinal tract of humans and other mammals, where they ferment many diet-derived carbohydrates that cannot be digested by their host. To extend our understanding of bifidobacterial carbohydrate utilisation, we investigated th...
ORGANISM(S): Bifidobacterium breve 
2013-08-16 | E-GEOD-47448 | biostudies-arrayexpress
TranscriptomicsA two-component regulatory system controls serpin expression in Bifidobacterium breve UCC2003.
This work reports on the identification and molecular characterization of a two-component regulatory system (2CRS), encoded by serRK, which is believed to control the expression of the ser2003 locus in Bifidobacterium breve UCC2003. The ser2003 locus consists of two genes, Bbr_1319 (sagA) and Bbr_13...
ORGANISM(S): Bifidobacterium breve UCC2003 
2012-08-28 | E-GEOD-37835 | biostudies-arrayexpress
TranscriptomicsCross-feeding by Bifidobacterium breve UCC2003 during Bifidobacterium bifidum PRL2010 growth on a mucin-based medium.
Bifidobacteria constitute commensal bacteria that commonly inhabit the mammalian gastro intestinal tract. The gut commensal Bifidobacterium breve UCC2003 was previously shown to utilise a variety of plant/diet-derived carbohydrates, including cellodextrin, starch and galactan. In the current study, ...
ORGANISM(S): Bifidobacterium breve UCC2003 
2014-12-17 | E-GEOD-59013 | biostudies-arrayexpress
TranscriptomicsMetabolism of sialic acid by Bifidobacterium breve UCC2003
Bifidobacteria constitute a specific group of commensal bacteria which inhabit the gastrointestinal tract of humans and other mammals. Bifidobacterium breve UCC2003 has previously been shown to utilise several plant-derived carbohydrates that include cellodextrins, starch and galactan. In the curren...
ORGANISM(S): Bifidobacterium breve UCC2003 
2014-05-29 | E-GEOD-56291 | biostudies-arrayexpress
TranscriptomicsRegulation of the raffinose and melezitose utilization operons of B. breve UCC2003
Members of the genus Bifidobacterium are Gram-positive bacteria which are commonly found in the gastrointestinal tract (GIT) of mammals, including humans. Growth of bifidobacteria has been shown to be selectively stimulated by various carbohydrates found in the human diet. To extend our understandi...
ORGANISM(S): Bifidobacterium breve UCC2003 
2014-04-20 | E-GEOD-50211 | biostudies-arrayexpress
TranscriptomicsSYNTHESIS OF THE INTERSPECIES SIGNALING MOLECULE AUTOINDUCER-2 PLAYS AN IMPORTANT ROLE IN THE ANTI-MICROBIAL EFFECT OF BIFIDOBACTERIA
In the present study we show that a functional luxS gene is present in all members of the genus Bifidobacterium and that AI-2 production by Bifidobacterium breve UCC2003 is necessary to confer protection against Salmonella infection in Caenorhabditis elegans. Mutants carrying a disrupted luxS gene c...
ORGANISM(S): Bifidobacterium breve UCC2003 
2015-12-31 | E-GEOD-49880 | biostudies-arrayexpress
TranscriptomicsDiscovering novel bile protection systems in Bifidobacterium breve UCC2003 through functional genomics
Tolerance of gut commensals to bile salt exposure is an important feature for their survival in and colonization of the intestinal environment. A transcriptomic approach was employed to study the response of Bifidobacterium breve UCC2003 to bile, allowing the identification of a number of bile-induc...
ORGANISM(S): Bifidobacterium breve UCC2003 
2011-12-16 | E-GEOD-31032 | biostudies-arrayexpress
TranscriptomicsBile-inducible membrane protein mediates the bile resistance phenotype of Bifidobacterium breve UCC2003
Bbr_0838 from Bifidobacterium breve UCC2003 encodes a 683 residue membrane protein, that contains a permease domain displaying similarity to transporters belonging to the major facilitator superfamily, as well as a CBS (cystathionine beta synthase) domain. The high level of similarity to bile-efflux...
ORGANISM(S): Bifidobacterium breve UCC2003 
2012-02-20 | E-GEOD-31224 | biostudies-arrayexpress
TranscriptomicsMetabolism of a plant derived galactose-containing polysaccharide by Bifidobacterium breve UCC2003
In this study, we describe the functional characterisation of the B. breve UCC2003 gal locus, which is dedicated to the utilisation of galactan, a plant-derived polysaccharide. Using a combination of molecular approaches we conclude that the galA gene of B. breve UCC2003 encodes a beta-1,4-endogalac...
ORGANISM(S): Bifidobacterium breve UCC2003 
2012-05-16 | E-GEOD-21865 | biostudies-arrayexpress
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