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ProteomicsLSD1 inhibition induces differentiation and cell death in Merkel cell carcinoma
Merkel cell carcinoma (MCC) is a highly aggressive, neuroendocrine skin cancer that lacks actionable mutations, which could be utilized for targeted therapies. Epigenetic regulators governing cell identity may represent unexplored therapeutic entry points. Here, we targeted epigenetic regulators in ...
ORGANISM(S): Homo sapiens (Human) 
2020-11-03 | PXD020590 | Pride
Hmg20b Mcc Lsd1 Epigenetics Kdm1a 
TranscriptomicsHigh-resolution analysis of copy number changes in circulating and disseminated tumor cells in breast cancer patients
The aim of this study was to establish a single-cell array comparative genomic hybridization (SCaCGH) method providing in-depth genomic analysis of circulating tumor cells (CTCs) and disseminated tumor cells (DTCs). The robustness and resolution limits of the method were estimated with different cel...
ORGANISM(S): Homo sapiens 
2012-11-19 | E-GEOD-27574 | biostudies-arrayexpress
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