Microtubule nucleation by γ-tubulin ring complexes (γ-TuRCs) must be spatiotemporally controlled to avoid major cell division errors. γ-TuRCs are activated by the centrosome-specific binding of a highly conserved Centrosomin Motif 1 (CM1) domain, but how binding is prevented in the cytosol remains u...
ORGANISM(S): Drosophila melanogaster (Fruit fly)