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ProteomicsPolysulfur-based bulking of dynamin-related protein 1 prevents ischemic sulfide catabolism and heart failure
The presence of redox-active molecules containing catenated sulfur atoms (supersulfide) in living organisms has led to a review of the concepts of redox biology and its translational strategy. Glutathione (GSH) is the body’s primary detoxifier and antioxidant, and its oxidized form (GSSG) has been c...
ORGANISM(S): Rattus norvegicus (Rat) 
2024-11-16 | PXD053562 | Pride
Mitochondria Glutathionylation Heart failure Drp1 Supersulfide catabolism 
Proteomics2H-Thiopyran-2-Thione Sulfine, a Compound For Converting H2S to HSOH/H2S2 and Increasing Intracellular Sulfane Sulfur Levels
Reactive sulfane sulfur species such as persulfides (RSSH) and H2S2 are important redox regulators and closely linked to H2S signaling. However, the study of these species is still challenging due to their instability, high reactivity, and the lack of suitable donors to produce these species. Herein...
ORGANISM(S): Oryctolagus Cuniculus (ncbitaxon:9986) 
2024-02-07 | MSV000094034 | MassIVE
ProteomicsSupersulphide airway protection in viral and chronic lung diseases
Supersulphides (inorganic and organic sulphides with sulphur catenation) manifest diverse physiological functions. These supersulphides are mainly generated from mitochondrial cysteinyl-tRNA synthetase (CARS2) that functions as a principal cysteine persulphide synthase (CPERS). Here we found power...
ORGANISM(S): Escherichia coli 
2023-07-14 | PXD043607 | Pride
3clpro Plpro Spike protein 
UnknownLight responsive hydrogen selenide (H<sub>2</sub>Se)/hydrogen diselenide (H<sub>2</sub>Se<sub>2</sub>) donors: applied for protein <i>S</i>-selenylation on PRDX6.
Not available
S-EPMC12452010 | biostudies-literature
UnknownDevelopment of a method for isolating brain capillaries from a single neonatal mouse brain and comparison of proteomic profiles between neonatal and adult brain capillaries.
Not available
S-EPMC10290343 | biostudies-literature
UnknownOptimal direct oral anticoagulant for upper gastrointestinal endoscopic submucosal dissection.
Not available
S-EPMC11717785 | biostudies-literature
UnknownInvestigation of Maternal Diet and FADS1 Polymorphism Associated with Long-Chain Polyunsaturated Fatty Acid Compositions in Human Milk.
Not available
S-EPMC9143760 | biostudies-literature
UnknownAssociation of four imprinting disorders and ART.
Not available
S-EPMC6367766 | biostudies-literature
UnknownBehavioral activation for depression in patients with advanced cancer: study protocol for a multicenter randomized controlled trial.
Not available
S-EPMC10173594 | biostudies-literature
ProteomicsBrain microvascular endothelial cells: PODXL KD
The purpose of the present study was, therefore, to explore the effect of PODXL-knockdown on the protein expression and transport function in the immortalized human BMECs (hCMEC/D3) as a human BBB model. We established PODXL-knockdown hCMEC/D3 cells, and protein expressions were comprehensively anal...
ORGANISM(S): Homo Sapiens (human) 
2022-03-11 | PXD030652 | JPOST Repository
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