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Multi-batch isobaric labeling experiments are frequently applied for clinical and pharmaceutical studies of large sample cohorts. To tackle the critical issue of missing values in such studies, we introduce the ProSIMSIt pipeline. It combines the advantages of tandem mass spectrum clustering via SIM...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD057211 | Pride
To investigate whether samples digested with trypsin, GluC, or AspN benefit from PSM rescoring, we rescored a timsTOF Pro dataset that was digested using different proteases. For detailed information on data acquisition, please refer to the original publication by Fossati et al. (PXD025671). In brie...
ORGANISM(S): Mycobacterium Tuberculosis (ncbitaxon:1773) Homo Sapiens (ncbitaxon:9606) 
2024-01-30 | MSV000093954 | MassIVE
To compare the rescoring performance on Orbitrap versus timsTOF data, we utilized a comparison dataset comprising both HLA-I and HLA-II peptides measured on an Orbitrap and on a timsTOF. For detailed information on data acquisition, please refer to the original publication by Gravel et al. (PXD03878...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-07-17 | MSV000092461 | MassIVE
We built and characterised a mass spectrometer capable of performing CID (both beam type and resonant type), UVPD, EID and ECD in an automated fashion during an LCMS type experiment. We exploited this ability to generate large datasets through multienzyme deep proteomics experiments for characterisa...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) Homo sapiens (Human) Escherichia coli 
2026-03-13 | PXD065289 | Pride
The SAGA transcriptional co-activator complex regulates gene expression through histone acetylation at promoters, mediated by its histone acetyl transferase, KAT2A. While its structure and function have been extensively investigated, how the stability of individual subunits of SAGA, including KAT2A,...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2026-03-16 | PXD065443 | Pride
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