Sort   by:  
 Page size 
ProteomicsCampylobacter jejuni MOMP carbene footprinting
Using carbene footprinting, we map the MOMP-QPLEX interaction and show by complementary in silico docking that QPLEX enters the porin channel through interactions at the extracellular face, translocates down the channel through a dipole transverse electric field towards the opposite end and is relea...
ORGANISM(S): Campylobacter jejuni subsp. jejuni NCTC 11168-PO 
2022-09-26 | PXD035978 | Pride
Carbene footprinting Campylobacter jejuni Lc-ms/ms 
ProteomicsCarbene footprinting reveals binding interfaces of a multimeric membrane spanning protein
Mapping the interaction sites between membrane spanning proteins is a key challenge in structural biology. Here we develop and apply carbene footprinting technology to identify the interfacial sites of a trimeric membrane protein. We show how the footprinting probe is effectively incorporated into d...
ORGANISM(S): Escherichia coli 
2017-09-29 | PXD007207 | Pride
Footprinting Protein Carbene Lc-ms Membrane 
ProteomicsMapping the Interaction between Eukaryotic Initiation Factor 4A (eIF4A) and the Inhibitor Hippuristanol Using Carbene Footprinting and Mass Spectrometry
Protein-ligand interactions are central to protein activity and cell functionality. Improved knowledge of these relationships greatly benefits our understanding of key biological processes and aids in rational drug design towards the treatment of clinically relevant diseases. Carbene footprinting is...
ORGANISM(S): Homo sapiens (Human) 
2021-08-25 | PXD025105 | Pride
Protein footprinting Mapping ligand binding Carbene labelling 
ProteomicsCarbene Footprinting Accurately Maps Binding Sites in Protein-Ligand and Protein-Protein Interactions
Specific interactions between proteins and their binding partners are fundamental to life processes. Differential protein footprinting using a new and efficient, photo-activated aryltrifluromethylcarbene probe together with mass spectrometry has been employed to identify protein-ligand and protein-p...
ORGANISM(S): Homo sapiens (Human) Gallus gallus (Chicken) 
2016-12-19 | PXD004971 | Pride
Lysozyme Carbene footprinting Usp5 Covalent labelling 
ProteomicsMass spectrometry insights into a tandem ubiquitinâ??binding domain hybrid engineered for the selective recognition of unanchored polyubiquitin
Unanchored polyubiquitin chains are emerging as important regulators of cellular physiology with diverse roles paralleling those of substrate-conjugated polyubiquitin. However tools able to discriminate unanchored polyubiquitin chains of different isopeptide linkages have not been described. We desc...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-22 | MSV000079990 | MassIVE
Sort   by:  
 Page size