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GenomicsInter-organellar and systemic survival responses to impaired mitochondrial matrix protein import in skeletal muscle
Inter-organellar and systemic survival responses to impaired mitochondrial matrix protein import in skeletal muscle
PRJNA815842 | ENA
ProteomicsInteractors of trapped protein from mitochondria from HeLa cells with stalled import TMT-MS
This study explores the consequences of import failure in mammalian cells; wherein, blocking the import machinery has profound effects on mitochondrial ultra-structure and dynamics, but, surprisingly, does not impact import. The explanation is an astonishing response involving intercellular mitochon...
ORGANISM(S): Homo sapiens (Human) 
2024-05-24 | PXD040098 | Pride
Mitochondria Hela Import Galactose 
ProteomicsCharting Organellar Importomes by Quantitative Mass Spectrometry -SAM50
Protein import into organelles is essential for all eukaryotes and facilitated by multi-protein translocation machineries. Analyzing whether a protein is transported into an organelle is largely restricted to single constituents. This renders knowledge about imported proteins incomplete, limiting ou...
ORGANISM(S): Trypanosoma brucei 
2017-06-14 | PXD004979 | Pride
Trypanosoma brucei Proteomics Glycosomes Organellar protein import Mitochondria Silac Importomics Rnai-mediated protein knockdown 
ProteomicsCharting Organellar Importomes by Quantitative Mass Spectrometry – PEX14c
Protein import into organelles is essential for all eukaryotes and facilitated by multi-protein translocation machineries. Analyzing whether a protein is transported into an organelle is largely restricted to single constituents. This renders knowledge about imported proteins incomplete, limiting ou...
ORGANISM(S): Trypanosoma brucei 
2017-06-14 | PXD004972 | Pride
Trypanosoma brucei Proteomics Glycosomes Organellar protein import Mitochondria Silac Importomics Rnai-mediated protein knockdown 
ProteomicsCharting Organellar Importomes by Quantitative Mass Spectrometry - ATOM40p
Protein import into organelles is essential for all eukaryotes and facilitated by multi-protein translocation machineries. Analyzing whether a protein is transported into an organelle is largely restricted to single constituents. This renders knowledge about imported proteins incomplete, limiting ou...
ORGANISM(S): Trypanosoma brucei 
2017-06-14 | PXD004917 | Pride
Trypanosoma brucei Proteomics Glycosomes Organellar protein import Mitochondria Silac Importomics Rnai-mediated protein knockdown 
ProteomicsCharting Organellar Importomes by Quantitative Mass Spectrometry – ATOM40c
Protein import into organelles is essential for all eukaryotes and facilitated by multi-protein translocation machineries. Analyzing whether a protein is transported into an organelle is largely restricted to single constituents. This renders knowledge about imported proteins incomplete, limiting ou...
ORGANISM(S): Trypanosoma brucei 
2017-06-14 | PXD004950 | Pride
Trypanosoma brucei Proteomics Glycosomes Organellar protein import Mitochondria Silac Importomics Rnai-mediated protein knockdown 
ProteomicsCharting Organellar Importomes by Quantitative Mass Spectrometry - ATOM40 whole cells
Protein import into organelles is essential for all eukaryotes and facilitated by multi-protein translocation machineries. Analyzing whether a protein is transported into an organelle is largely restricted to single constituents. This renders knowledge about imported proteins incomplete, limiting ou...
ORGANISM(S): Trypanosoma brucei 
2017-06-14 | PXD005725 | Pride
Trypanosoma brucei Proteomics Glycosomes Organellar protein import Mitochondria Silac Importomics Rnai-mediated protein knockdown 
UnknownInter-organellar and systemic responses to impaired mitochondrial matrix protein import in skeletal muscle.
Not available
S-EPMC9534917 | biostudies-literature
ProteomicsCharting Organellar Importomes by Quantitative Mass Spectrometry - ERV1 organelle-enriched fractions
Protein import into organelles is essential for all eukaryotes and facilitated by multi-protein translocation machineries. Analyzing whether a protein is transported into an organelle is largely restricted to single constituents. This renders knowledge about imported proteins incomplete, limiting ou...
ORGANISM(S): Trypanosoma brucei 
2017-06-14 | PXD005730 | Pride
Trypanosoma brucei Proteomics Organellar protein import Mitochondria Stable dimethyl labeling Importomics Rnai-mediated protein knockdown 
TranscriptomicsInter-organellar and systemic survival responses to impaired mitochondrial matrix protein import in skeletal muscle
Mitochondrial functions are largely performed by proteins imported from cytosol. Impaired protein import in mitochondria affects the maintenance of intra-mitochondrial anabolic and energy metabolic pathways. It leads to cytosolic accumulation of mistargeted proteins and activation of cellular stress...
ORGANISM(S): Mus musculus 
2022-10-04 | GSE198540 | GEO
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